General Structure Information 1rz4 EIF3K crystal structure of human eif3k 2.1Å AUTH Z.WEI,P.ZHANG,Z.ZHOU,Z.CHENG,M.WAN,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN EIF3K, THE FIRST STRUCTURE OFTITL 2 EIF3 SUBUNITSREF J.BIOL.CHEM. V. 279 34983 2004REFN ISSN 0021-9258PMID 15180986DOI 10.1074/JBC.M405158200 Variant Set Distributions Mapped Variants
General Structure Information 2mc3 MUS81 nmr solution structure of the winged-helix domain from mus81 structure-specific endonuclease -1.0Å AUTH A.J.FADDEN,S.SCHALBETTER,M.BOWLES,R.HARRIS,J.LALLY,A.M.CARR,AUTH 2 N.Q.MCDONALDTITL A WINGED HELIX DOMAIN IN HUMAN MUS81 BINDS DNA AND MODULATESTITL 2 THE ENDONUCLEASE ACTIVITY OF MUS81 COMPLEXES.REF NUCLEIC ACIDS RES. V. 41 9741 2013REFN ISSN 0305-1048PMID 23982516DOI 10.1093/NAR/GKT760 Variant Set Distributions Mapped Variants
General Structure Information 4c9y SKA1 structural basis for the microtubule binding of the human kinetochore ska complex 2.01Å AUTH M.A.ABAD,B.MEDINA,A.SANTAMARIA,J.ZOU,C.PLASBERG-HILL,AUTH 2 A.MADHUMALAR,U.JAYACHANDRAN,P.M.REDLI,J.RAPPSILBER,E.A.NIGG,AUTH 3 A.A.JEYAPRAKASHTITL STRUCTURAL BASIS FOR MICROTUBULE RECOGNITION BY THE HUMANTITL 2 KINETOCHORE SKA COMPLEX.REF NAT.COMMUN. V. 5 2964 2014REFN ISSN 2041-1723PMID 24413531DOI 10.1038/NCOMMS3964 Variant Set Distributions Mapped Variants
General Structure Information 1cf7 TFDP2 structural basis of dna recognition by the heterodimeric cell cycle transcription factor e2f-dp 2.6Å AUTH N.ZHENG,E.FRAENKEL,C.O.PABO,N.P.PAVLETICHTITL STRUCTURAL BASIS OF DNA RECOGNITION BY THETITL 2 HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTORTITL 3 E2F-DP.REF GENES DEV. V. 13 666 1999REFN ISSN 0890-9369PMID 10090723 Variant Set Distributions Mapped Variants
General Structure Information 3qx3 TOP2B human topoisomerase iibeta in complex with dna and etoposide 2.16Å AUTH C.C.WU,T.K.LI,L.FARH,L.Y.LIN,T.S.LIN,Y.J.YU,T.J.YEN,AUTH 2 C.W.CHIANG,N.L.CHANTITL STRUCTURAL BASIS OF TYPE II TOPOISOMERASE INHIBITION BY THETITL 2 ANTICANCER DRUG ETOPOSIDEREF SCIENCE V. 333 459 2011REFN ISSN 0036-8075PMID 21778401DOI 10.1126/SCIENCE.1204117 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 3qx3 TOP2B human topoisomerase iibeta in complex with dna and etoposide 2.16Å AUTH C.C.WU,T.K.LI,L.FARH,L.Y.LIN,T.S.LIN,Y.J.YU,T.J.YEN,AUTH 2 C.W.CHIANG,N.L.CHANTITL STRUCTURAL BASIS OF TYPE II TOPOISOMERASE INHIBITION BY THETITL 2 ANTICANCER DRUG ETOPOSIDEREF SCIENCE V. 333 459 2011REFN ISSN 0036-8075PMID 21778401DOI 10.1126/SCIENCE.1204117 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1i27 GTF2F1 crystal structure of the c-terminal domain of the rap74 subunit of human transcription factor iif (tfiif) 1.02Å AUTH K.KAMADA,J.DE ANGELIS,R.G.ROEDER,S.K.BURLEYTITL CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THETITL 2 RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF.REF PROC.NATL.ACAD.SCI.USA V. 98 3115 2001REFN ISSN 0027-8424PMID 11248041DOI 10.1073/PNAS.051631098 Variant Set Distributions Mapped Variants
General Structure Information 2k86 FOXO3 solution structure of foxo3a forkhead domain -1.0Å AUTH F.WANG,C.B.MARSHALL,K.YAMAMOTO,G.Y.LI,M.J.PLEVIN,AUTH 2 H.YOU,T.W.MAK,M.IKURATITL BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF ANTITL 2 INTRAMOLECULAR INTERACTION IN FOXO3A AND ITSTITL 3 BINDING WITH P53.REF J.MOL.BIOL. V. 384 590 2008REFN ISSN 0022-2836PMID 18824006DOI 10.1016/J.JMB.2008.09.025 Variant Set Distributions Mapped Variants