Assessment of Structural Intolerance and Durability
General Structure Information 4afl ING4 the crystal structure of the ing4 dimerization domain reveals the functional organization of the ing family of chromatin binding proteins. 2.28Å AUTH S.CULURGIONI,I.G.MUNOZ,A.MORENO,A.PALACIOS,M.VILLATE,AUTH 2 I.PALMERO,G.MONTOYA,F.J.BLANCOTITL CRYSTAL STRUCTURE OF INHIBITOR OF GROWTH 4 (ING4)TITL 2 DIMERIZATION DOMAIN REVEALS FUNCTIONAL ORGANIZATION OF INGTITL 3 FAMILY OF CHROMATIN-BINDING PROTEINS.REF J.BIOL.CHEM. V. 287 10876 […]
General Structure Information 1ixd CYLD solution structure of the cap-gly domain from human cylindromatosis tomour-suppressor cyld -1.0Å AUTH K.SAITO,T.KIGAWA,S.KOSHIBA,K.SATO,Y.MATSUO,AUTH 2 A.SAKAMOTO,T.TAKAGI,M.SHIROUZU,T.YABUKI,E.NUNOKAWA,AUTH 3 E.SEKI,T.MATSUDA,M.AOKI,Y.MIYATA,N.HIRAKAWA,AUTH 4 M.INOUE,T.TERADA,T.NAGASE,R.KIKUNO,M.NAKAYAMA,AUTH 5 O.OHARA,A.TANAKA,S.YOKOYAMATITL THE CAP-GLY DOMAIN OF CYLD ASSOCIATES WITH THETITL 2 PROLINE-RICH SEQUENCE IN NEMO/IKKGAMMAREF STRUCTURE V. 12 1719 2004REFN ISSN 0969-2126PMID 15341735DOI 10.1016/J.STR.2004.07.012 Variant Set Distributions Mapped Variants
General Structure Information 4a63 TP53BP2 crystal structure of the p73-aspp2 complex at 2.6a resolution 2.27Å AUTH P.CANNING,F.VON DELFT,A.N.BULLOCKTITL STRUCTURAL BASIS FOR ASPP2 RECOGNITION BY THE TUMORTITL 2 SUPPRESSOR P73.REF J.MOL.BIOL. V. 423 515 2012REFN ISSN 0022-2836PMID 22917970DOI 10.1016/J.JMB.2012.08.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4avp ETV1 crystal structure of the dna-binding domain of human etv1. 1.82Å AUTH C.D.O.COOPER,J.A.NEWMAN,H.AITKENHEAD,C.K.ALLERSTON,AUTH 2 O.GILEADITITL STRUCTURES OF THE ETS DOMAINS OF TRANSCRIPTION FACTORS ETV1,TITL 2 ETV4, ETV5 AND FEV: DETERMINANTS OF DNA BINDING AND REDOXTITL 3 REGULATION BY DISULFIDE BOND FORMATION.REF J.BIOL.CHEM. V. 290 13692 2015REFN ISSN 0021-9258PMID 25866208DOI 10.1074/JBC.M115.646737 Variant […]