Assessment of Structural Intolerance and Durability
General Structure Information 4ec8 CCNT1 structure of full length cdk9 in complex with cyclint and drb 3.6Å AUTH S.BAUMLI,A.J.HOLE,L.Z.WANG,M.E.NOBLE,J.A.ENDICOTTTITL THE CDK9 TAIL DETERMINES THE REACTION PATHWAY OF POSITIVETITL 2 TRANSCRIPTION ELONGATION FACTOR B.REF STRUCTURE V. 20 1788 2012REFN ISSN 0969-2126PMID 22959624DOI 10.1016/J.STR.2012.08.011 Variant Set Distributions Mapped Variants
General Structure Information 4gqb PRMT5 crystal structure of the human prmt5:mep50 complex 2.06Å AUTH S.ANTONYSAMY,Z.BONDAY,R.M.CAMPBELL,B.DOYLE,Z.DRUZINA,AUTH 2 T.GHEYI,B.HAN,L.N.JUNGHEIM,Y.QIAN,C.RAUCH,M.RUSSELL,AUTH 3 J.M.SAUDER,S.R.WASSERMAN,K.WEICHERT,F.S.WILLARD,A.ZHANG,AUTH 4 S.EMTAGETITL CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 109 17960 2012REFN ISSN 0027-8424PMID 23071334DOI 10.1073/PNAS.1209814109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants