Assessment of Structural Intolerance and Durability
General Structure Information 4dm8 RARB crystal structure of rarb lbd in complex with 9cis retinoic acid 2.3Å AUTH J.OSZ,Y.BRELIVET,C.PELUSO-ILTIS,V.CURA,S.EILER,M.RUFF,AUTH 2 W.BOURGUET,N.ROCHEL,D.MORASTITL STRUCTURAL BASIS FOR A MOLECULAR ALLOSTERIC CONTROLTITL 2 MECHANISM OF COFACTOR BINDING TO NUCLEAR RECEPTORS.REF PROC.NATL.ACAD.SCI.USA V. 109 E588 2012REFN ISSN 0027-8424PMID 22355136DOI 10.1073/PNAS.1118192109 Variant Set Distributions Mapped Variants
General Structure Information 3o35 TRIM24 crystal structure of trim24 phd-bromo complexed with h3(23-31)k27ac peptide 1.76Å AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants