Assessment of Structural Intolerance and Durability
General Structure Information 1nbq F11R crystal structure of human junctional adhesion molecule type 1 2.9Å AUTH A.E.PROTA,J.A.CAMPBELL,P.SCHELLING,J.C.FORREST,AUTH 2 M.J.WATSON,T.R.PETERS,M.AURRAND-LIONS,B.A.IMHOF,AUTH 3 T.S.DERMODY,T.STEHLETITL CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESIONTITL 2 MOLECULE 1: IMPLICATIONS FOR REOVIRUS BINDINGREF PROC.NATL.ACAD.SCI.USA V. 100 5366 2003REFN ISSN 0027-8424PMID 12697893DOI 10.1073/PNAS.0937718100 Variant Set Distributions Mapped Variants
General Structure Information 2osg TJP2 solution structure and binding property of the domain- swapped dimer of zo2pdz2 -1.0Å AUTH J.W.WU,Y.S.YANG,J.H.ZHANG,P.JI,W.J.DU,P.JIANG,AUTH 2 D.H.XIE,H.D.HUANG,M.WU,G.Z.ZHANG,J.H.WU,Y.Y.SHITITL DOMAIN-SWAPPED DIMERIZATION OF THE SECOND PDZTITL 2 DOMAIN OF ZO2 MAY PROVIDE A STRUCTURAL BASIS FORTITL 3 THE POLYMERIZATION OF CLAUDINSREF J.BIOL.CHEM. V. 282 35988 2007REFN ISSN 0021-9258PMID 17897942DOI 10.1074/JBC.M703826200 Variant Set Distributions […]
General Structure Information 3bpu MAGI1 crystal structure of the 3rd pdz domain of human membrane associated guanylate kinase, c677s and c709s double mutant 1.6Å AUTH E.S.PILKA,V.HOZJAN,C.COOPER,A.C.W.PIKE,J.ELKINS,D.A.DOYLE,AUTH 2 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANETITL 2 ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2kpk MAGI1 magi-1 pdz1 -1.0Å AUTH S.CHARBONNIER,Y.NOMINE,J.RAMIREZ,K.LUCK,A.CHAPELLE,AUTH 2 R.H.STOTE,G.TRAVE,B.KIEFFER,R.A.ATKINSONTITL THE STRUCTURAL AND DYNAMIC RESPONSE OF MAGI-1 PDZ1 WITHTITL 2 NON-CANONICAL DOMAIN BOUNDARIES TO BINDING OF HUMANTITL 3 PAPILLOMAVIRUS (HPV) E6REF J.MOL.BIOL. 2011REFN ESSN 1089-8638PMID 21238461DOI 10.1016/J.JMB.2011.01.015 Variant Set Distributions Mapped Variants
General Structure Information 2r4h MAGI1 crystal structure of a c1190s mutant of the 6th pdz domain of human membrane associated guanylate kinase 2.05Å AUTH E.UGOCHUKWU,E.S.PILKA,V.HOZJAN,K.L.KAVANAGH,C.COOPER,AUTH 2 A.C.W.PIKE,J.M.ELKINS,D.A.DOYLE,F.VON DELFT,M.SUNDSTROM,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.M.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF A C1190S MUTANT OF THE 6TH PDZ DOMAINTITL 2 OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s […]
General Structure Information 2db5 INADL solution structure of the first pdz domain of inad-like protein -1.0Å AUTH K.INOUE,C.KUROSAKI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST PDZ DOMAIN OFTITL 2 INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ehr INADL solution structure of the sixth pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SIXTH PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dm8 INADL solution structure of the eighth pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE EIGHTH PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dmz INADL solution structure of the third pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kom PARD3 solution structure of humar par-3b pdz2 (residues 451-549) -1.0Å AUTH D.R.JENSEN,C.WOYTOVICH,M.LI,P.DUVNJAK,M.S.CASSIDY,AUTH 2 R.O.FREDERICK,L.F.BERGEMAN,F.C.PETERSON,B.F.VOLKMANTITL RAPID, ROBOTIC, SMALL-SCALE PROTEIN PRODUCTION FORTITL 2 NMR SCREENING AND STRUCTURE DETERMINATION.REF PROTEIN SCI. V. 19 570 2010REFN ISSN 0961-8368PMID 20073081DOI 10.1002/PRO.335 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants