General Structure Information 3u5o HIST1H3D crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants
General Structure Information 1u7f SMAD3 crystal structure of the phosphorylated smad3/smad4 heterotrimeric complex 2.6Å AUTH B.M.CHACKO,B.Y.QIN,A.TIWARI,G.SHI,S.LAM,AUTH 2 L.J.HAYWARD,M.DE CAESTECKER,K.LINTITL STRUCTURAL BASIS OF HETEROMERIC SMAD PROTEINTITL 2 ASSEMBLY IN TGF-BETA SIGNALINGREF MOL.CELL V. 15 813 2004REFN ISSN 1097-2765PMID 15350224DOI 10.1016/J.MOLCEL.2004.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3kfd TGFBR1 ternary complex of tgf-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily 3.0Å AUTH S.RADAEV,Z.ZOU,T.HUANG,E.M.LAFER,A.P.HINCK,P.D.SUNTITL TERNARY COMPLEX OF TRANSFORMING GROWTH FACTOR-BETA1 REVEALSTITL 2 ISOFORM-SPECIFIC LIGAND RECOGNITION AND RECEPTORTITL 3 RECRUITMENT IN THE SUPERFAMILY.REF J.BIOL.CHEM. V. 285 14806 2010REFN ISSN 0021-9258PMID 20207738DOI 10.1074/JBC.M109.079921 Variant Set Distributions Mapped Variants
General Structure Information 2r53 BMP6 crystal structure analysis of bone morphogenetic protein-6 variant b2 (b2-bmp-6) 2.1Å AUTH S.SAREMBA,J.NICKEL,A.SEHER,A.KOTZSCH,W.SEBALD,AUTH 2 T.D.MUELLERTITL TYPE I RECEPTOR BINDING OF BONE MORPHOGENETICTITL 2 PROTEIN 6 IS DEPENDENT ON N-GLYCOSYLATION OF THETITL 3 LIGAND.REF FEBS J. V. 275 172 2007REFN ISSN 1742-464XPMID 18070108DOI 10.1111/J.1742-4658.2007.06187.X Variant Set Distributions Mapped Variants
General Structure Information 2b0u FST the structure of the follistatin:activin complex 2.8Å AUTH T.B.THOMPSON,T.F.LERCH,R.W.COOK,T.K.WOODRUFF,T.S.JARDETZKYTITL THE STRUCTURE OF THE FOLLISTATIN:ACTIVIN COMPLEX REVEALSTITL 2 ANTAGONISM OF BOTH TYPE I AND TYPE II RECEPTOR BINDING.REF DEV.CELL V. 9 535 2005REFN ISSN 1534-5807PMID 16198295DOI 10.1016/J.DEVCEL.2005.09.008 Variant Set Distributions Mapped Variants
General Structure Information 2qcq BMP3 crystal structure of bone morphogenetic protein-3 (bmp-3) 2.21Å AUTH G.P.ALLENDORPH,M.J.ISAACS,Y.KAWAKAMI,J.C.BELMONTE,S.CHOETITL BMP-3 AND BMP-6 STRUCTURES ILLUMINATE THE NATURE OF BINDINGTITL 2 SPECIFICITY WITH RECEPTORS.REF BIOCHEMISTRY V. 46 12238 2007REFN ISSN 0006-2960PMID 17924656DOI 10.1021/BI700907K Variant Set Distributions Mapped Variants