Assessment of Structural Intolerance and Durability
General Structure Information 1w24 VPS29 crystal structure of human vps29 2.1Å AUTH D.WANG,M.GUO,Z.LIANG,J.FAN,Z.ZHU,J.ZANG,Z.ZHU,X.LI,AUTH 2 M.TENG,L.NIU,Y.DONG,P.LIUTITL CRYSTAL STRUCTURE OF HUMAN VACUOLAR PROTEINTITL 2 SORTING PROTEIN 29 REVEALS ATITL 3 PHOSPHODIESTERASE/NUCLEASE-LIKE FOLD AND TWOTITL 4 PROTEIN-PROTEIN INTERACTION SITES.REF J.BIOL.CHEM. V. 280 22962 2005REFN ISSN 0021-9258PMID 15788412DOI 10.1074/JBC.M500464200 Variant Set Distributions Mapped Variants
General Structure Information 3iq2 SNX7 human sorting nexin 7, phox homology (px) domain 1.7Å AUTH T.KARLBERG,M.WISNIEWSKA,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,A.KALLAS,T.KOTENYOVA,AUTH 4 A.KOTZSCH,P.KRAULIS,M.MOCHE,T.K.NIELSEN,P.NORDLUND,T.NYMAN,AUTH 5 C.PERSSON,A.K.ROOS,P.SCHUTZ,M.I.SIPONEN,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,H.SCHULERTITL HUMAN SORTING NEXIN 7, PHOX HOMOLOGY (PX) DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ae4 UBAP1 the ubap1 subunit of escrt-i interacts with ubiquitin via a novel souba domain 1.65Å AUTH M.AGROMAYOR,N.SOLER,A.CABALLE,T.KUECK,S.M.FREUND,M.D.ALLEN,AUTH 2 M.BYCROFT,O.PERISIC,Y.YE,B.MCDONALD,H.SCHEEL,K.HOFMANN,AUTH 3 S.J.D.NEIL,J.MARTIN-SERRANO,R.L.WILLIAMSTITL THE UBAP1 SUBUNIT OF ESCRT-I INTERACTS WITH UBIQUITIN VIA ATITL 2 SOUBA DOMAIN.REF STRUCTURE V. 20 414 2012REFN ISSN 0969-2126PMID 22405001DOI 10.1016/J.STR.2011.12.013 Variant Set Distributions Mapped Variants
General Structure Information 3f6k SORT1 crystal structure of the vps10p domain of human sortilin/nts3 in complex with neurotensin 2.0Å AUTH E.M.QUISTGAARD,P.MADSEN,M.K.GROFTEHAUGE,P.NISSEN,AUTH 2 C.M.PETERSEN,S.S.THIRUPTITL LIGANDS BIND TO SORTILIN IN THE TUNNEL OF A TEN-BLADEDTITL 2 BETA-PROPELLER DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 16 96 2009REFN ISSN 1545-9993PMID 19122660DOI 10.1038/NSMB.1543 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3cuq VPS25 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 2dm4 SORL1 solution structure of the second fn3 domain of human sorla/lr11 -1.0Å AUTH T.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN OFTITL 2 HUMAN SORLA/LR11REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2zme SNF8 integrated structural and functional model of the human escrt-ii complex 2.9Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 3cuq VPS36 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 1upt GOLGA4 structure of a complex of the golgin-245 grip domain with arl1 1.7Å AUTH B.PANIC,O.PERISIC,D.B.VEPRINTSEV,R.L.WILLIAMS,AUTH 2 S.MUNROTITL STRUCTURAL BASIS FOR ARL1-DEPENDENT TARGETING OFTITL 2 HOMODIMERIC GRIP DOMAINS TO THE GOLGI APPARATUSREF MOL.CELL V. 12 863 2003REFN ISSN 1097-2765PMID 14580338DOI 10.1016/S1097-2765(03)00356-3 Variant Set Distributions Mapped Variants
General Structure Information 3lui SNX17 crystal structure of the snx17 px domain with bound sulphate 1.8Å AUTH R.GHAI,M.MOBLI,S.J.NORWOOD,A.BUGARCIC,R.D.TEASDALE,G.F.KING,AUTH 2 B.M.COLLINSTITL PHOX HOMOLOGY BAND 4.1/EZRIN/RADIXIN/MOESIN-LIKE PROTEINSTITL 2 FUNCTION AS MOLECULAR SCAFFOLDS THAT INTERACT WITH CARGOTITL 3 RECEPTORS AND RAS GTPASESREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490PMID 21512128DOI 10.1073/PNAS.1017110108 Variant Set Distributions Mapped Variants