Assessment of Structural Intolerance and Durability
General Structure Information 3e9l PRPF8 crystal structure of human prp8, residues 1755-2016 1.95Å AUTH V.PENA,A.ROZOV,P.FABRIZIO,R.LUHRMANN,M.C.WAHLTITL STRUCTURE AND FUNCTION OF AN RNASE H DOMAIN AT THE HEART OFTITL 2 THE SPLICEOSOME.REF EMBO J. V. 27 2929 2008REFN ISSN 0261-4189PMID 18843295DOI 10.1038/EMBOJ.2008.209 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4kit PRPF8 crystal structure of human brr2 in complex with the prp8 jab1/mpn domain 3.6Å AUTH S.MOZAFFARI-JOVIN,T.WANDERSLEBEN,K.F.SANTOS,C.L.WILL,AUTH 2 R.LUHRMANN,M.C.WAHLTITL INHIBITION OF RNA HELICASE BRR2 BY THE C-TERMINAL TAIL OFTITL 2 THE SPLICEOSOMAL PROTEIN PRP8.REF SCIENCE V. 341 80 2013REFN ISSN 0036-8075PMID 23704370DOI 10.1126/SCIENCE.1237515 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2cpn TARBP2 solution structure of the second dsrbd of tar rna-binding protein 2 -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND DSRBD OF TARTITL 2 RNA-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jzx PCBP2 pcbp2 kh1-kh2 domains -1.0Å AUTH Z.DU,S.FENN,R.TJHEN,T.JAMESTITL STRUCTURE OF THE FIRST AND SECOND KH DOMAINS OF HUMAN POLY-CTITL 2 BINDING PROTEIN-2 REVEALS INSIGHTS INTO ITS REGULATORYTITL 3 MECHANISMSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 4ed5 ELAVL1 crystal structure of the two n-terminal rrm domains of hur complexed with rna 2.0Å AUTH H.WANG,F.ZENG,Q.LIU,H.LIU,Z.LIU,L.NIU,M.TENG,X.LITITL THE STRUCTURE OF THE ARE-BINDING DOMAINS OF HU ANTIGEN RTITL 2 (HUR) UNDERGOES CONFORMATIONAL CHANGES DURING RNA BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 69 373 2013REFN ISSN 0907-4449PMID 23519412DOI 10.1107/S0907444912047828 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 4a8x RNPS1 structure of the core asap complex 1.9Å AUTH A.G.MURACHELLI,J.EBERT,C.BASQUIN,H.LE HIR,E.CONTITITL THE STRUCTURE OF THE ASAP CORE COMPLEX REVEALS THETITL 2 EXISTENCE OF A PININ-CONTAINING PSAP COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 19 378 2012REFN ISSN 1545-9993PMID 22388736DOI 10.1038/NSMB.2242 Variant Set Distributions Mapped Variants
General Structure Information 2dt6 SF3A1 solution structure of the first surp domain of human splicing factor sf3a120 -1.0Å AUTH K.KUWASAKO,F.HE,M.INOUE,A.TANAKA,S.SUGANO,AUTH 2 P.GUENTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SURP DOMAINS AND THETITL 2 SUBUNIT-ASSEMBLY MECHANISM WITHIN THE SPLICINGTITL 3 FACTOR SF3A COMPLEX IN 17S U2 SNRNPREF STRUCTURE V. 14 1677 2006REFN ISSN 0969-2126PMID 17098193DOI 10.1016/J.STR.2006.09.009 Variant Set […]