Assessment of Structural Intolerance and Durability
General Structure Information 3eij PDCD4 crystal structure of pdcd4 2.8Å AUTH P.G.LOH,H.-S.YANG,M.A.WALSH,Q.WANG,X.WANG,Z.CHENG,D.LIU,AUTH 2 H.SONGTITL STRUCTURAL BASIS FOR TRANSLATIONAL INHIBITION BY THE TUMOURTITL 2 SUPPRESSOR PDCD4REF EMBO J. V. 28 274 2009REFN ISSN 0261-4189PMID 19153607DOI 10.1038/EMBOJ.2008.278 Variant Set Distributions Mapped Variants
General Structure Information 1x0f HNRNPD complex structure of the c-terminal rna-binding domain of hnrnp d(auf1) with telomeric dna -1.0Å AUTH Y.ENOKIZONO,Y.KONISHI,K.NAGATA,K.OUHASHI,S.UESUGI,AUTH 2 F.ISHIKAWA,M.KATAHIRATITL STRUCTURE OF HNRNP D COMPLEXED WITHTITL 2 SINGLE-STRANDED TELOMERE DNA AND UNFOLDING OF THETITL 3 QUADRUPLEX BY HETEROGENEOUS NUCLEARTITL 4 RIBONUCLEOPROTEIN D.REF J.BIOL.CHEM. V. 280 18862 2005REFN ISSN 0021-9258PMID 15734733DOI 10.1074/JBC.M411822200 Variant […]
General Structure Information 3bor EIF4A2 crystal structure of the deadc domain of human translation initiation factor 4a-2 1.85Å AUTH P.SCHUTZ,T.KARLBERG,S.VAN DEN BERG,R.COLLINS,L.LEHTIO,AUTH 2 M.HOGBOM,L.HOLMBERG-SCHIAVONE,W.TEMPEL,H.W.PARK,AUTH 3 M.HAMMARSTROM,M.MOCHE,A.G.THORSELL,H.SCHULERTITL COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX RNATITL 2 HELICASES.REF PLOS ONE V. 5 12791 2010REFN ESSN 1932-6203PMID 20941364DOI 10.1371/JOURNAL.PONE.0012791 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2jzx PCBP2 pcbp2 kh1-kh2 domains -1.0Å AUTH Z.DU,S.FENN,R.TJHEN,T.JAMESTITL STRUCTURE OF THE FIRST AND SECOND KH DOMAINS OF HUMAN POLY-CTITL 2 BINDING PROTEIN-2 REVEALS INSIGHTS INTO ITS REGULATORYTITL 3 MECHANISMSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1hzd AUH crystal structure of human auh protein, an rna-binding homologue of enoyl-coa hydratase 2.2Å AUTH K.KURIMOTO,S.FUKAI,O.NUREKI,Y.MUTO,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN AUH PROTEIN, ATITL 2 SINGLE-STRANDED RNA BINDING HOMOLOG OF ENOYL-COATITL 3 HYDRATASE.REF STRUCTURE V. 9 1253 2001REFN ISSN 0969-2126PMID 11738050DOI 10.1016/S0969-2126(01)00686-4 Variant Set Distributions Mapped Variants
General Structure Information 3llm DHX9 crystal structure analysis of a rna helicase 2.8Å AUTH P.SCHUTZ,E.WAHLBERG,T.KARLBERG,M.HAMMARSTROM,R.COLLINS,AUTH 2 A.FLORES,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN RNA HELICASE A (DHX9): STRUCTURALTITL 2 BASIS FOR UNSELECTIVE NUCLEOTIDE BASE BINDING IN A DEAD-BOXTITL 3 VARIANT PROTEIN.REF J.MOL.BIOL. V. 400 768 2010REFN ISSN 0022-2836PMID 20510246DOI 10.1016/J.JMB.2010.05.046 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bg0 SEC13 architecture of a coat for the nuclear pore membrane 3.15Å AUTH K.C.HSIA,P.STAVROPOULOS,G.BLOBEL,A.HOELZTITL ARCHITECTURE OF A COAT FOR THE NUCLEAR PORETITL 2 MEMBRANE.REF CELL(CAMBRIDGE,MASS.) V. 131 1313 2007REFN ISSN 0092-8674PMID 18160040DOI 10.1016/J.CELL.2007.11.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2zu6 EIF4A1 crystal structure of the eif4a-pdcd4 complex 2.8Å AUTH J.H.CHANG,Y.H.CHO,S.Y.SOHN,J.M.CHOI,A.KIM,Y.C.KIM,AUTH 2 S.K.JANG,Y.CHOTITL CRYSTAL STRUCTURE OF THE EIF4A-PDCD4 COMPLEXREF PROC.NATL.ACAD.SCI.USA V. 106 3148 2009REFN ISSN 0027-8424PMID 19204291DOI 10.1073/PNAS.0808275106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dpr VLDLR human rhinovirus 2 bound to a concatamer of the vldl receptor module v3 3.5Å AUTH J.QUEROL-AUDI,T.KONECSNI,J.POUS,O.CARUGO,I.FITA,N.VERDAGUER,AUTH 2 D.BLAASTITL MINOR GROUP HUMAN RHINOVIRUS-RECEPTOR INTERACTIONS: GEOMETRYTITL 2 OF MULTIMODULAR ATTACHMENT AND BASIS OF RECOGNITIONREF FEBS LETT. V. 583 235 2009REFN ISSN 0014-5793PMID 19073182DOI 10.1016/J.FEBSLET.2008.12.014 Variant Set Distributions Mapped Variants