Assessment of Structural Intolerance and Durability
General Structure Information 4dm8 RARB crystal structure of rarb lbd in complex with 9cis retinoic acid 2.3Å AUTH J.OSZ,Y.BRELIVET,C.PELUSO-ILTIS,V.CURA,S.EILER,M.RUFF,AUTH 2 W.BOURGUET,N.ROCHEL,D.MORASTITL STRUCTURAL BASIS FOR A MOLECULAR ALLOSTERIC CONTROLTITL 2 MECHANISM OF COFACTOR BINDING TO NUCLEAR RECEPTORS.REF PROC.NATL.ACAD.SCI.USA V. 109 E588 2012REFN ISSN 0027-8424PMID 22355136DOI 10.1073/PNAS.1118192109 Variant Set Distributions Mapped Variants
General Structure Information 1dsz RARA structure of the rxr/rar dna-binding domain heterodimer in complex with the retinoic acid response element dr1 1.7Å AUTH F.RASTINEJAD,T.WAGNER,Q.ZHAO,S.KHORASANIZADEHTITL STRUCTURE OF THE RXR-RAR DNA-BINDING COMPLEX ONTITL 2 THE RETINOIC ACID RESPONSE ELEMENT DR1.REF EMBO J. V. 19 1045 2000REFN ISSN 0261-4189PMID 10698945DOI 10.1093/EMBOJ/19.5.1045 Variant Set Distributions Mapped Variants
General Structure Information 1lq8 SERPINA5 crystal structure of cleaved protein c inhibitor 2.4Å AUTH J.A.HUNTINGTON,M.KJELLBERG,J.STENFLOTITL CRYSTAL STRUCTURE OF PROTEIN C INHIBITOR PROVIDES INSIGHTSTITL 2 INTO HORMONE BINDING AND HEPARIN ACTIVATIONREF STRUCTURE V. 11 205 2003REFN ISSN 0969-2126PMID 12575940DOI 10.1016/S0969-2126(02)00944-9 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1lq8 SERPINA5 crystal structure of cleaved protein c inhibitor 2.4Å AUTH J.A.HUNTINGTON,M.KJELLBERG,J.STENFLOTITL CRYSTAL STRUCTURE OF PROTEIN C INHIBITOR PROVIDES INSIGHTSTITL 2 INTO HORMONE BINDING AND HEPARIN ACTIVATIONREF STRUCTURE V. 11 205 2003REFN ISSN 0969-2126PMID 12575940DOI 10.1016/S0969-2126(02)00944-9 Variant Set Distributions Mapped Variants