Assessment of Structural Intolerance and Durability
General Structure Information 3no8 BTBD2 crystal structure of the phr domain from human btbd2 protein 2.2Å AUTH P.SAMPATHKUMARTITL CRYSTAL STRUCTURE OF THE PHR DOMAIN FROM HUMAN BTBD2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dls PASK crystal structure of human pas kinase bound to adp 2.3Å AUTH C.K.KIKANI,S.A.ANTONYSAMY,J.B.BONANNO,R.ROMERO,F.F.ZHANG,AUTH 2 M.RUSSELL,T.GHEYI,M.IIZUKA,S.EMTAGE,J.M.SAUDER,B.E.TURK,AUTH 3 S.K.BURLEY,J.RUTTERTITL STRUCTURAL BASES OF PAS DOMAIN-REGULATED KINASE (PASK)TITL 2 ACTIVATION IN THE ABSENCE OF ACTIVATION LOOPTITL 3 PHOSPHORYLATION.REF J.BIOL.CHEM. V. 285 41034 2010REFN ISSN 0021-9258PMID 20943661DOI 10.1074/JBC.M110.157594 Variant Set Distributions Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3r0n PVRL2 crystal structure of the immunoglobulin variable domain of nectin-2 1.3Å AUTH D.SAMANTA,U.A.RAMAGOPAL,R.RUBINSTEIN,V.VIGDOROVICH,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF NECTIN-2 REVEALS DETERMINANTS OF HOMOPHILIC ANDTITL 2 HETEROPHILIC INTERACTIONS THAT CONTROL CELL-CELL ADHESION.REF PROC.NATL.ACAD.SCI.USA V. 109 14836 2012REFN ISSN 0027-8424PMID 22927415DOI 10.1073/PNAS.1212912109 Variant Set Distributions Mapped Variants
General Structure Information 2r0b STYX crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein 1.6Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,T.P.DILORENZO,AUTH 2 V.MALASHKEVICH,S.R.WASSERMAN,S.SWAMINATHAN,S.ESWARAMOORTHY,AUTH 3 R.AGARWAL,D.KUMARAN,M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,AUTH 4 J.ALVARADO,U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 5 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Mapped Variants
General Structure Information 4hwn FCRLA crystal structure of the second ig-c2 domain of human fc-receptor like a (fcrla), isoform 9 [nysgrc-005836] 2.01Å AUTH P.R.KUMAR,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE SECOND IG-C2 DOMAIN OF THE HUMANTITL 2 FC-RECEPTOR LIKE A, ISOFORM 9 [NYSGRC-005836]REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4gos VTCN1 crystal structure of human b7-h4 igv-like domain 1.59Å AUTH V.VIGDOROVICH,U.RAMAGOPAL,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF HUMAN B7-H4 IGV-LIKE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2i1y PTPRN crystal structure of the phosphatase domain of human ptp ia-2 2.23Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,T.P.DILORENZO,AUTH 2 V.MALASHKEVICH,S.R.WASSERMAN,S.SWAMINATHAN,S.ESWARAMOORTHY,AUTH 3 R.AGARWAL,D.KUMARAN,M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,AUTH 4 J.ALVARADO,U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 5 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASESREF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2g59 PTPRO crystal structure of the catalytic domain of protein tyrosine phosphatase from homo sapiens 2.19Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,AUTH 2 T.P.DILORENZO,V.MALASHKEVICH,S.R.WASSERMAN,AUTH 3 S.SWAMINATHAN,S.ESWARAMOORTHY,R.AGARWAL,D.KUMARAN,AUTH 4 M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,J.ALVARADO,AUTH 5 U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 6 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants