General Structure Information 2jbh PRTFDC1 human phosphoribosyl transferase domain containing 1 1.7Å AUTH M.WELIN,L.EGEBLAD,A.JOHANSSON,P.STENMARK,L.WANG,S.FLODIN,AUTH 2 T.NYMAN,L.TRESAUGUES,T.KOTENYOVA,I.JOHANSSON,S.ERIKSSON,AUTH 3 H.EKLUND,P.NORDLUNDTITL STRUCTURAL AND FUNCTIONAL STUDIES OF THE HUMANTITL 2 PHOSPHORIBOSYLTRANSFERASE DOMAIN CONTAINING PROTEIN 1.REF FEBS J. V. 277 4920 2010REFN ISSN 1742-464XPMID 21054786DOI 10.1111/J.1742-4658.2010.07897.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 2vxo GMPS human gmp synthetase in complex with xmp 2.5Å AUTH M.WELIN,L.LEHTIO,A.JOHANSSON,S.FLODIN,T.NYMAN,AUTH 2 L.TRESAUGUES,M.HAMMARSTROM,S.GRASLUND,P.NORDLUNDTITL SUBSTRATE SPECIFICITY AND OLIGOMERIZATION OF HUMANTITL 2 GMP SYNTHETASEREF J.MOL.BIOL. V. 425 4323 2013REFN ISSN 0022-2836PMID 23816837DOI 10.1016/J.JMB.2013.06.032 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1pkx ATIC crystal structure of human atic in complex with xmp 1.9Å AUTH D.W.WOLAN,C.G.CHEONG,S.E.GREASLEY,I.A.WILSONTITL STRUCTURAL INSIGHTS INTO THE HUMAN AND AVIAN IMPTITL 2 CYCLOHYDROLASE MECHANISM VIA CRYSTAL STRUCTURESTITL 3 WITH THE BOUND XMP INHIBITOR.REF BIOCHEMISTRY V. 43 1171 2004REFN ISSN 0006-2960PMID 14756553DOI 10.1021/BI030162I Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2v40 ADSS human adenylosuccinate synthetase isozyme 2 in complex with gdp 1.9Å AUTH M.WELIN,M.MOCHE,C.ARROWSMITH,H.BERGLUND,R.BUSAM,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,B.M.HALLBERG,AUTH 4 L.HOLMBERG-SCHIAVONE,I.JOHANSSON,A.KALLAS,AUTH 5 T.KARLBERG,T.KOTENYOVA,L.LEHTIO,T.NYMAN,D.OGG,AUTH 6 C.PERSSON,J.SAGEMARK,P.STENMARK,M.SUNDSTROM,AUTH 7 A.G.THORSELL,S.VAN-DEN-BERG,J.WEIGELT,P.NORDLUNDTITL HUMAN ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 INTITL 2 COMPLEX WITH GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2v9y GART human aminoimidazole ribonucleotide synthetase 2.1Å AUTH M.WELIN,J.G.GROSSMANN,S.FLODIN,T.NYMAN,P.STENMARK,AUTH 2 L.TRESAUGUES,T.KOTENYOVA,I.JOHANSSON,P.NORDLUND,L.LEHTIOTITL STRUCTURAL STUDIES OF TRI-FUNCTIONAL HUMAN GART.REF NUCLEIC ACIDS RES. V. 38 7308 2010REFN ISSN 0305-1048PMID 20631005DOI 10.1093/NAR/GKQ595 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants