Assessment of Structural Intolerance and Durability
General Structure Information 3ihr UCHL5 crystal structure of uch37 2.95Å AUTH S.E.BURGIE,C.A.BINGMAN,A.B.SONI,G.N.PHILLIPSTITL STRUCTURAL CHARACTERIZATION OF HUMAN UCH37.REF PROTEINS 2011REFN ESSN 1097-0134PMID 21953935DOI 10.1002/PROT.23147 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2lgr OARD1 solution structure of human protein c6orf130, a putative macro domain -1.0Å AUTH F.C.PETERSON,D.CHEN,B.L.LYTLE,M.N.ROSSI,I.AHEL,J.M.DENU,AUTH 2 B.F.VOLKMANTITL ORPHAN MACRODOMAIN PROTEIN (HUMAN C6ORF130) IS ANTITL 2 O-ACYL-ADP-RIBOSE DEACYLASE: SOLUTION STRUCTURE ANDTITL 3 CATALYTIC PROPERTIES.REF J.BIOL.CHEM. V. 286 35955 2011REFN ISSN 0021-9258PMID 21849506DOI 10.1074/JBC.M111.276238 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1tvg HSPB11 x-ray structure of human pp25 gene product, hspc034. northeast structural genomics target hr1958. 1.6Å AUTH T.A.RAMELOT,S.RAMAN,A.P.KUZIN,R.XIAO,L.C.MA,AUTH 2 T.B.ACTON,J.F.HUNT,G.T.MONTELIONE,D.BAKER,AUTH 3 M.A.KENNEDYTITL IMPROVING NMR PROTEIN STRUCTURE QUALITY BY ROSETTATITL 2 REFINEMENT: A MOLECULAR REPLACEMENT STUDY.REF PROTEINS V. 75 147 2009REFN ISSN 0887-3585PMID 18816799DOI 10.1002/PROT.22229 Variant Set Distributions Mapped Variants
General Structure Information 2h1s GRHPR crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiens 2.45Å AUTH E.BITTO,G.E.WESENBERG,G.N.PHILLIPS JR.,C.A.BINGMAN,AUTH 2 CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL CRYSTAL STRUCTURE OF A GLYOXYLATE/HYDROXYPYRUVATE REDUCTASETITL 2 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1sgo GSKIP nmr structure of the human c14orf129 gene product, hspc210. northeast structural genomics target hr969. -1.0Å AUTH T.A.RAMELOT,J.R.CORT,R.XIAO,L.-Y.SHIH,L.-C.MA,AUTH 2 T.B.ACTON,G.T.MONTELIONE,M.A.KENNEDYTITL NMR STRUCTURE OF THE HUMAN C14ORF129 GENE PRODUCT,TITL 2 HSPC210. NORTHEAST STRUCTURAL GENOMICS TARGETTITL 3 HR969.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ab1 AAMDC x-ray structure of gene product from homo sapiens hs.95870 2.59Å AUTH CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL X-RAY STRUCTURE OF GENE PRODUCT FROM HOMO SAPIENS HS.95870REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2q4k C11orf68 ensemble refinement of the protein crystal structure of gene product from homo sapiens hs.433573 2.5Å AUTH E.J.LEVIN,D.A.KONDRASHOV,G.E.WESENBERG,G.N.PHILLIPSTITL ENSEMBLE REFINEMENT OF PROTEIN CRYSTAL STRUCTURES:TITL 2 VALIDATION AND APPLICATION.REF STRUCTURE V. 15 1040 2007REFN ISSN 0969-2126PMID 17850744DOI 10.1016/J.STR.2007.06.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dcy C12orf5 crystal structure a tp53-induced glycolysis and apoptosis regulator protein from homo sapiens. 1.75Å AUTH J.G.MCCOY,C.A.BINGMAN,G.E.WESENBERG,AUTH 2 G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE A TP53-INDUCED GLYCOLYSIS ANDTITL 2 APOPTOSIS REGULATOR PROTEIN FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1yzg ARL5B structure of human adp-ribosylation factor-like 8 2.0Å AUTH A.ATANASSOVA,J.CHOE,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.PARKTITL STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 8REF TO BE PUBLISHED 2005REFN Variant Set Distributions Mapped Variants