Assessment of Structural Intolerance and Durability
General Structure Information 2ror VAV1 solution structure of the vav1 sh2 domain complexed with a tyrosine-phosphorylated peptide from slp76 -1.0Å AUTH T.KASAI,M.TANAKA,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE VAV1 SH2 DOMAINTITL 2 COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDETITL 3 FROM SLP76REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lco CSF1R inhibitor bound to a dfg-out structure of the kinase domain of csf-1r 3.4Å AUTH M.J.MEYERS,M.PELC,S.KAMTEKAR,J.DAY,G.I.PODA,M.K.HALL,AUTH 2 M.L.MICHENER,B.A.REITZ,K.J.MATHIS,B.S.PIERCE,M.D.PARIKH,AUTH 3 D.A.MISCHKE,S.A.LONG,J.J.PARLOW,D.R.ANDERSON,A.THORARENSENTITL STRUCTURE-BASED DRUG DESIGN ENABLES CONVERSION OF A DFG-INTITL 2 BINDING CSF-1R KINASE INHIBITOR TO A DFG-OUT BINDING MODE.REF BIOORG.MED.CHEM.LETT. V. 20 1543 2010REFN ISSN 0960-894XPMID 20137931DOI 10.1016/J.BMCL.2010.01.078 Variant Set Distributions Pathogenic […]