General Structure Information 1u7t HSD17B10 crystal structure of abad/hsd10 with a bound inhibitor 2.0Å AUTH C.R.KISSINGER,P.A.REJTO,L.A.PELLETIER,J.A.THOMSON,AUTH 2 R.E.SHOWALTER,M.A.ABREO,C.S.AGREE,S.MARGOSIAK,AUTH 3 J.J.MENG,R.M.AUST,D.VANDERPOOL,B.LI,AUTH 4 A.TEMPCZYK-RUSSELL,J.E.VILLAFRANCATITL CRYSTAL STRUCTURE OF HUMAN ABAD/HSD10 WITH A BOUNDTITL 2 INHIBITOR: IMPLICATIONS FOR DESIGN OF ALZHEIMERSTITL 3 DISEASE THERAPEUTICSREF J.MOL.BIOL. V. 342 943 2004REFN ISSN 0022-2836PMID 15342248DOI 10.1016/J.JMB.2004.07.071 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3czv CA13 crystal structure of the human carbonic anhydrase xiii in complex with acetazolamide 2.0Å AUTH A.DI FIORE,S.M.MONTI,M.HILVO,S.PARKKILA,V.ROMANO,A.SCALONI,AUTH 2 C.PEDONE,A.SCOZZAFAVA,C.T.SUPURAN,G.DE SIMONETITL CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE XIII AND ITSTITL 2 COMPLEX WITH THE INHIBITOR ACETAZOLAMIDE.REF PROTEINS V. 74 164 2008REFN ISSN 0887-3585PMID 18618712DOI 10.1002/PROT.22144 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4ja8 IDH2 complex of mitochondrial isocitrate dehydrogenase r140q mutant with agi-6780 inhibitor 1.55Å AUTH F.WANG,J.TRAVINS,B.DELABARRE,V.PENARD-LACRONIQUE,S.SCHALM,AUTH 2 E.HANSEN,K.STRALEY,A.KERNYTSKY,W.LIU,C.GLISER,H.YANG,AUTH 3 S.GROSS,E.ARTIN,V.SAADA,E.MYLONAS,C.QUIVORON,AUTH 4 J.POPOVICI-MULLER,J.O.SAUNDERS,F.G.SALITURO,S.YAN,S.MURRAY,AUTH 5 W.WEI,Y.GAO,L.DANG,M.DORSCH,S.AGRESTA,D.P.SCHENKEIN,AUTH 6 S.A.BILLER,S.M.SU,S.DE BOTTON,K.E.YENTITL TARGETED INHIBITION OF MUTANT IDH2 IN LEUKEMIA CELLS INDUCESTITL 2 CELLULAR DIFFERENTIATION.REF SCIENCE V. 340 622 2013REFN ISSN 0036-8075PMID 23558173DOI 10.1126/SCIENCE.1234769 Variant Set Distributions Ripley’s K […]
General Structure Information 3ml5 CA7 crystal structure of the c183s/c217s mutant of human ca vii in complex with acetazolamide 2.05Å AUTH A.DI FIORE,E.TRUPPO,C.T.SUPURAN,V.ALTERIO,N.DATHAN,AUTH 2 F.BOOTORABI,S.PARKKILA,S.M.MONTI,G.DE SIMONETITL CRYSTAL STRUCTURE OF THE C183S/C217S MUTANT OF HUMAN CA VIITITL 2 IN COMPLEX WITH ACETAZOLAMIDEREF BIOORG.MED.CHEM.LETT. V. 20 5023 2010REFN ISSN 0960-894XPMID 20688517DOI 10.1016/J.BMCL.2010.07.051 Variant Set Distributions Mapped Variants
General Structure Information 4ekc RGS2 structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c) 7.4Å AUTH M.R.NANCE,B.KREUTZ,V.M.TESMER,R.STERNE-MARR,T.KOZASA,AUTH 2 J.J.TESMERTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE REGULATOR OF GTITL 2 PROTEIN SIGNALING 2-G ALPHA Q COMPLEX.REF STRUCTURE V. 21 438 2013REFN ISSN 0969-2126PMID 23434405DOI 10.1016/J.STR.2012.12.016 Variant Set Distributions Mapped Variants