Assessment of Structural Intolerance and Durability
General Structure Information 2vpd PYGO1 decoding of methylated histone h3 tail by the pygo-bcl9 wnt signaling complex 2.77Å AUTH M.FIEDLER,M.J.SANCHEZ-BARRENA,M.NEKRASOV,AUTH 2 J.MIESZCZANEK,V.RYBIN,J.MULLER,P.EVANS,M.BIENZTITL DECODING OF METHYLATED HISTONE H3 TAIL BY THETITL 2 PYGO- BCL9 WNT SIGNALING COMPLEX.REF MOL.CELL V. 30 507 2008REFN ISSN 1097-2765PMID 18498752DOI 10.1016/J.MOLCEL.2008.03.011 Variant Set Distributions Mapped Variants
General Structure Information 3rsn ASH2L crystal structure of the n-terminal region of human ash2l 2.1Å AUTH Y.CHEN,B.WAN,K.C.WANG,F.CAO,Y.YANG,A.PROTACIO,Y.DOU,AUTH 2 H.Y.CHANG,M.LEITITL CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF HUMAN ASH2LTITL 2 SHOWS A WINGED-HELIX MOTIF INVOLVED IN DNA BINDING.REF EMBO REP. V. 12 797 2011REFN ISSN 1469-221XPMID 21660059DOI 10.1038/EMBOR.2011.101 Variant Set Distributions Mapped Variants
General Structure Information 4cos ZMYND8 crystal structure of the phd-bromo-pwwp cassette of human prkcbp1 1.67Å AUTH P.FILIPPAKOPOULOSTITL CRYSTAL STRUCTURE OF THE PHD-BROMO-PWWP CASSETTE OF HUMANTITL 2 PRKCBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3u5n TRIM33 crystal structure of the complex of trim33 phd-bromo and h3(1-20) k9me3k14ac histone peptide 1.95Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2e6s UHRF2 solution structure of the phd domain in ring finger protein 107 -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TERADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PHD DOMAIN IN RINGTITL 2 FINGER PROTEIN 107REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4llb KAT6A crystal structure of moz double phd finger histone h3k14ac complex 2.5Å AUTH I.DREVENY,S.E.DEEVES,J.FULTON,B.YUE,M.MESSMER,AUTH 2 A.BHATTACHARYA,H.M.COLLINS,D.M.HEERYTITL THE DOUBLE PHD FINGER DOMAIN OF MOZ/MYST3 INDUCESTITL 2 ALPHA-HELICAL STRUCTURE OF THE HISTONE H3 TAIL TO FACILITATETITL 3 ACETYLATION AND METHYLATION SAMPLING AND MODIFICATION.REF NUCLEIC ACIDS RES. V. 42 822 2014REFN ISSN 0305-1048PMID 24150941DOI […]
General Structure Information 2ysm KMT2C solution structure of the first and second phd domain from myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND SECOND PHDTITL 2 DOMAIN FROM MYELOID/LYMPHOID OR MIXED-LINEAGETITL 3 LEUKEMIA PROTEIN 3 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2m85 SHPRH phd domain from human shprh -1.0Å AUTH L.E.MACHADO,Y.PUSTOVALOVA,A.C.KILE,A.POZHIDAEVA,AUTH 2 K.A.CIMPRICH,F.C.ALMEIDA,I.BEZSONOVA,D.M.KORZHNEVTITL PHD DOMAIN FROM HUMAN SHPRH.REF J.BIOMOL.NMR V. 56 393 2013REFN ISSN 0925-2738PMID 23907177DOI 10.1007/S10858-013-9758-2 Variant Set Distributions Mapped Variants
General Structure Information 2l5u CHD4 structure of the first phd finger (phd1) from chd4 (mi2b) -1.0Å AUTH R.E.MANSFIELD,C.A.MUSSELMAN,A.H.KWAN,S.S.OLIVER,A.L.GARSKE,AUTH 2 F.DAVRAZOU,J.M.DENU,T.G.KUTATELADZE,J.P.MACKAYTITL PLANT HOMEODOMAIN (PHD) FINGERS OF CHD4 ARE HISTONETITL 2 H3-BINDING MODULES WITH PREFERENCE FOR UNMODIFIED H3K4 ANDTITL 3 METHYLATED H3K9REF J.BIOL.CHEM. V. 286 11779 2011REFN ISSN 0021-9258PMID 21278251DOI 10.1074/JBC.M110.208207 Variant Set Distributions Mapped Variants
General Structure Information 2ro1 TRIM28 nmr solution structures of human kap1 phd finger-bromodomain -1.0Å AUTH L.ZENG,K.L.YAP,A.V.IVANOV,X.WANG,S.MUJTABA,AUTH 2 O.PLOTNIKOVA,F.J.RAUSCHER,M.M.ZHOUTITL STRUCTURAL INSIGHTS INTO HUMAN KAP1 PHDTITL 2 FINGER-BROMODOMAIN AND ITS ROLE IN GENE SILENCINGREF NAT.STRUCT.MOL.BIOL. V. 15 626 2008REFN ISSN 1545-9993PMID 18488044DOI 10.1038/NSMB.1416 Variant Set Distributions Mapped Variants