General Structure Information 2vom TPI1 structural basis of human triosephosphate isomerase deficiency. mutation e104d and correlation to solvent perturbation. 1.85Å AUTH C.RODRIGUEZ-ALMAZAN,R.ARREOLA-ALEMON,AUTH 2 D.RODRIGUEZ-LARREA,B.AGUIRRE-LOPEZ,AUTH 3 M.T.DE GOMEZ-PUYOU,R.PEREZ-MONTFORT,M.COSTAS,AUTH 4 A.GOMEZ-PUYOU,A.TORRES-LARIOSTITL STRUCTURAL BASIS OF HUMAN TRIOSEPHOSPHATETITL 2 ISOMERASE DEFICIENCY: MUTATION E104D IS RELATED TOTITL 3 ALTERATIONS OF A CONSERVED WATER NETWORK AT THETITL 4 DIMER INTERFACE.REF J.BIOL.CHEM. […]
General Structure Information 2jkv PGD structure of human phosphogluconate dehydrogenase in complex with nadph at 2.53a 2.53Å AUTH S.S.NG,F.VON DELFT,E.S.PILKA,K.L.KAVANAGH,M.A.MCDONOUGH,AUTH 2 P.SAVITSKY,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,M.SUNDSTROM,AUTH 3 C.J.SCHOFIELD,U.OPPERMANNTITL STRUCTURE OF HUMAN PHOSPHOGLUCONATE DEHYDROGENASE INTITL 2 COMPLEX WITH NADPH AT 2.53AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4kxu TKT human transketolase in covalent complex with donor ketose d-fructose- 6-phosphate 0.98Å AUTH S.LUDTKE,P.NEUMANN,K.M.ERIXON,F.LEEPER,R.KLUGER,R.FICNER,AUTH 2 K.TITTMANNTITL SUB-ANGSTROM-RESOLUTION CRYSTALLOGRAPHY REVEALS PHYSICALTITL 2 DISTORTIONS THAT ENHANCE REACTIVITY OF A COVALENT ENZYMATICTITL 3 INTERMEDIATE.REF NAT CHEM V. 5 762 2013REFNPMID 23965678DOI 10.1038/NCHEM.1728 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]