Assessment of Structural Intolerance and Durability
General Structure Information 2ckk KIN high resolution crystal structure of the human kin17 c-terminal domain containing a kow motif kin17. 1.45Å AUTH A.LE MAIRE,M.SCHILTZ,E.A.STURA,G.PINON-LATAILLADE,AUTH 2 J.COUPRIE,M.MOUTIEZ,M.GONDRY,J.F.ANGULO,AUTH 3 S.ZINN-JUSTINTITL A TANDEM OF SH3-LIKE DOMAINS PARTICIPATES IN RNATITL 2 BINDING IN KIN17, A HUMAN PROTEIN ACTIVATED INTITL 3 RESPONSE TO GENOTOXICS.REF J.MOL.BIOL. V. 364 764 2006REFN ISSN […]
General Structure Information 2v1n KIN solution structure of the region 51-160 of human kin17 reveals a winged helix fold -1.0Å AUTH L.CARLIER,A.LE MAIRE,M.GONDRY,L.GUILHAUDIS,AUTH 2 I.MILAZZO,D.DAVOUST,J.COUPRIE,B.GILQUIN,AUTH 3 S.ZINN-JUSTINTITL SOLUTION STRUCTURE OF THE REGION 51-160 OF HUMANTITL 2 KIN17 REVEALS AN ATYPICAL WINGED HELIX DOMAINREF PROTEIN SCI. V. 16 2750 2007REFN ISSN 0961-8368PMID 18029424DOI 10.1110/PS.073079107 Variant Set […]
General Structure Information 2uz8 EEF1E1 the crystal structure of p18, human translation elongation factor 1 epsilon 1 2.0Å AUTH K.J.KIM,M.C.PARK,S.J.CHOI,Y.S.OH,E.C.CHOI,H.J.CHO,AUTH 2 M.H.KIM,S.H.KIM,D.W.KIM,S.KIM,B.S.KANGTITL DETERMINATION OF THREE-DIMENSIONAL STRUCTURE ANDTITL 2 RESIDUES OF THE NOVEL TUMOR SUPPRESSOR AIMP3/P18TITL 3 REQUIRED FOR THE INTERACTION WITH ATM.REF J.BIOL.CHEM. V. 283 14032 2008REFN ISSN 0021-9258PMID 18343821DOI 10.1074/JBC.M800859200 Variant Set Distributions Mapped […]
General Structure Information 2x8a NVL human nuclear valosin containing protein like (nvl), c- terminal aaa-atpase domain 2.6Å AUTH M.MOCHE,P.SCHUETZ,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,I.JOHANSSON,A.KALLAS,AUTH 4 T.KARLBERG,T.KOTENYOVA,P.KRAULIS,P.NORDLUND,AUTH 5 T.NYMAN,C.PERSSON,A.SEHIC,M.I.SIPONEN,L.SVENSSON,AUTH 6 A.G.THORSELL,L.TRESAUGUES,S.VANDENBERG,E.WAHLBERG,AUTH 7 J.WEIGELT,M.WELIN,M.WISNIEWSKA,H.SCHULERTITL HUMAN NUCLEAR VALOSIN CONTAINING PROTEIN LIKETITL 2 (NVL) , C-TERMINAL AAA-ATPASE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2zfu RRP8 structure of the methyltransferase-like domain of nucleomethylin 2.0Å AUTH A.MURAYAMA,K.OHMORI,A.FUJIMURA,H.MINAMI,K.YASUZAWA-TANAKA,AUTH 2 T.KURODA,S.OIE,H.DAITOKU,M.OKUWAKI,K.NAGATA,A.FUKAMIZU,AUTH 3 K.KIMURA,T.SHIMIZU,J.YANAGISAWATITL EPIGENETIC CONTROL OF RDNA LOCI IN RESPONSE TO INTRACELLULARTITL 2 ENERGY STATUSREF CELL(CAMBRIDGE,MASS.) V. 133 627 2008REFN ISSN 0092-8674PMID 18485871DOI 10.1016/J.CELL.2008.03.030 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1h3o TAF4 crystal structure of the human taf4-taf12 (tafii135-tafii20) complex 2.3Å AUTH S.WERTEN,A.MITSCHLER,C.ROMIER,Y.-G.GANGLOFF,AUTH 2 S.THUAULT,I.DAVIDSON,D.MORASTITL CRYSTAL STRUCTURE OF A SUBCOMPLEX OF HUMANTITL 2 TRANSCRIPTION FACTOR TFIID FORMED BY TATA BINDINGTITL 3 PROTEIN-ASSOCIATED FACTORS HTAF4 (HTAF(II)135) ANDTITL 4 HTAF12 (HTAF(II)20).REF J.BIOL.CHEM. V. 277 45502 2002REFN ISSN 0021-9258PMID 12237304DOI 10.1074/JBC.M206587200 Variant Set Distributions Mapped […]
General Structure Information 1h6f TBX3 human tbx3, a transcription factor responsible for ulnar-mammary syndrome , bound to a palindromic dna site 1.7Å AUTH M.COLL,J.G.SEIDMAN,C.W.MULLERTITL STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMANTITL 2 TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FORTITL 3 ULNAR- MAMMARY SYNDROMEREF STRUCTURE V. 10 343 2002REFN ISSN 0969-2126PMID 12005433DOI 10.1016/S0969-2126(02)00722-0 Variant Set Distributions […]