General Structure Information 4ad9 LACTB2 crystal structure of human lactb2. 2.6Å AUTH C.K.ALLERSTON,T.KROJER,O.GILEADITITL CRYSTAL STRUCTURE OF HUMAN LACTB2.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wya HMGCS2 crystal structure of human mitochondrial 3-hydroxy-3- methylglutaryl-coenzyme a synthase 2 (hmgcs2) 1.7Å AUTH N.SHAFQAT,A.TURNBULL,J.ZSCHOCKE,U.OPPERMANN,AUTH 2 W.W.YUETITL CRYSTAL STRUCTURES OF HUMAN HMG-COA SYNTHASETITL 2 ISOFORMS PROVIDE INSIGHTS INTO INHERITEDTITL 3 KETOGENESIS DISORDERS AND INHIBITOR DESIGN.REF J.MOL.BIOL. V. 398 497 2010REFN ISSN 0022-2836PMID 20346956DOI 10.1016/J.JMB.2010.03.034 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3p0l STAR human steroidogenic acute regulatory protein 3.4Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2w8r ALDH5A1 the crystal structure of human ssadh in complex with nad+ 2.4Å AUTH Y.-G.KIM,S.LEE,O.-S.KWON,S.-Y.PARK,S.-J.LEE,AUTH 2 B.-J.PARK,K.-J.KIMTITL REDOX-SWITCH MODULATION OF HUMAN SSADH BY DYNAMICTITL 2 CATALYTIC LOOP.REF EMBO J. V. 28 959 2009REFN ISSN 0261-4189PMID 19300440DOI 10.1038/EMBOJ.2009.40 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2×36 LONP1 structure of the proteolytic domain of the human mitochondrial lon protease 2.0Å AUTH J.GARCIA-NAFRIA,G.ONDROVICOVA,E.BLAGOVA,AUTH 2 V.M.LEVDIKOV,J.A.BAUER,C.K.SUZUKI,E.KUTEJOVA,AUTH 3 A.J.WILKINSON,K.S.WILSONTITL STRUCTURE OF THE CATALYTIC DOMAIN OF THE HUMANTITL 2 MITOCHONDRIAL LON PROTEASE: PROPOSED RELATION OFTITL 3 OLIGOMER FORMATION AND ACTIVITY.REF PROTEIN SCI. V. 19 987 2010REFN ISSN 0961-8368PMID 20222013DOI 10.1002/PRO.376 Variant Set […]
General Structure Information 4oe5 ALDH4A1 structure of human aldh4a1 crystallized in space group p21 1.95Å AUTH T.A.PEMBERTON,D.SRIVASTAVA,N.SANYAL,M.T.HENZL,D.F.BECKER,AUTH 2 J.J.TANNERTITL STRUCTURAL STUDIES OF YEAST DELTATITL 2 (1)-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1): ACTIVETITL 3 SITE FLEXIBILITY AND OLIGOMERIC STATE.REF BIOCHEMISTRY V. 53 1350 2014REFN ISSN 0006-2960PMID 24502590DOI 10.1021/BI500048B Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4dvq CYP11B2 structure of human aldosterone synthase, cyp11b2, in complex with deoxycorticosterone 2.49Å AUTH N.STRUSHKEVICH,A.A.GILEP,L.SHEN,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 S.A.USANOV,H.W.PARKTITL STRUCTURAL INSIGHTS INTO ALDOSTERONE SYNTHASE SUBSTRATETITL 2 SPECIFICITY AND TARGETED INHIBITION.REF MOL.ENDOCRINOL. V. 27 315 2013REFN ISSN 0888-8809PMID 23322723DOI 10.1210/ME.2012-1287 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3p1m FDX1 crystal structure of human ferredoxin-1 (fdx1) in complex with iron- sulfur cluster 2.54Å AUTH A.CHAIKUAD,C.JOHANSSON,T.KROJER,W.W.YUE,C.PHILLIPS,J.E.BRAY,AUTH 2 A.C.W.PIKE,J.R.C.MUNIZ,M.VOLLMAR,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,C.BOUNTRA,K.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN FERREDOXIN-1 (FDX1) IN COMPLEXTITL 2 WITH IRON-SULFUR CLUSTERREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4boc POLRMT structure of mitochondrial rna polymerase elongation complex 2.65Å AUTH K.SCHWINGHAMMER,A.C.M.CHEUNG,Y.I.MOROZOV,K.AGARONYAN,AUTH 2 D.TEMIAKOV,P.CRAMERTITL STRUCTURE OF HUMAN MITOCHONDRIAL RNA POLYMERASE ELONGATIONTITL 2 COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1298 2013REFN ISSN 1545-9993PMID 24096365DOI 10.1038/NSMB.2683 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants