Assessment of Structural Intolerance and Durability
General Structure Information 2f6n BPTF crystal structure of phd finger-linker-bromodomain fragment of human bptf in the free form 2.0Å AUTH H.LI,S.ILIN,W.WANG,E.M.DUNCAN,J.WYSOCKA,C.D.ALLIS,AUTH 2 D.J.PATELTITL MOLECULAR BASIS FOR SITE-SPECIFIC READ-OUT OFTITL 2 HISTONE H3K4ME3 BY THE BPTF PHD FINGER OF NURF.REF NATURE V. 442 91 2006REFN ISSN 0028-0836PMID 16728978DOI 10.1038/NATURE04802 Variant Set Distributions Mapped Variants
General Structure Information 2j2s KMT2A solution structure of the nonmethyl-cpg-binding cxxc domain of the leukaemia-associated mll histone methyltransferase -1.0Å AUTH M.D.ALLEN,C.G.GRUMMITT,C.HILCENKO,S.Y.MIN,AUTH 2 L.M.TONKIN,C.M.JOHNSON,S.M.FREUND,M.BYCROFT,AUTH 3 A.J.WARRENTITL SOLUTION STRUCTURE OF THE NONMETHYL-CPG-BINDINGTITL 2 CXXC DOMAIN OF THE LEUKAEMIA-ASSOCIATED MLLTITL 3 HISTONE METHYLTRANSFERASEREF EMBO J. V. 25 4503 2006REFN ISSN 0261-4189PMID 16990798DOI 10.1038/SJ.EMBOJ.7601340 Variant Set Distributions Mapped Variants
General Structure Information 3u5o HIST1H3H crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants
General Structure Information 3u5o HIST1H3J crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants
General Structure Information 3u5o HIST1H3D crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants
General Structure Information 3h7h SUPT4H1 crystal structure of the human transcription elongation factor dsif, hspt4/hspt5 (176-273) 1.55Å AUTH S.WENZEL,B.M.MARTINS,P.ROSCH,B.M.WOHRLTITL CRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION ELONGATIONTITL 2 FACTOR DSIF HSPT4 SUBUNIT IN COMPLEX WITH THE HSPT5TITL 3 DIMERIZATION INTERFACEREF BIOCHEM.J. V. 425 373 2010REFN ISSN 0264-6021PMID 19860741DOI 10.1042/BJ20091422 Variant Set Distributions Mapped Variants
General Structure Information 3llm DHX9 crystal structure analysis of a rna helicase 2.8Å AUTH P.SCHUTZ,E.WAHLBERG,T.KARLBERG,M.HAMMARSTROM,R.COLLINS,AUTH 2 A.FLORES,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN RNA HELICASE A (DHX9): STRUCTURALTITL 2 BASIS FOR UNSELECTIVE NUCLEOTIDE BASE BINDING IN A DEAD-BOXTITL 3 VARIANT PROTEIN.REF J.MOL.BIOL. V. 400 768 2010REFN ISSN 0022-2836PMID 20510246DOI 10.1016/J.JMB.2010.05.046 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2f6n BPTF crystal structure of phd finger-linker-bromodomain fragment of human bptf in the free form 2.0Å AUTH H.LI,S.ILIN,W.WANG,E.M.DUNCAN,J.WYSOCKA,C.D.ALLIS,AUTH 2 D.J.PATELTITL MOLECULAR BASIS FOR SITE-SPECIFIC READ-OUT OFTITL 2 HISTONE H3K4ME3 BY THE BPTF PHD FINGER OF NURF.REF NATURE V. 442 91 2006REFN ISSN 0028-0836PMID 16728978DOI 10.1038/NATURE04802 Variant Set Distributions Mapped Variants
General Structure Information 2j2s KMT2A solution structure of the nonmethyl-cpg-binding cxxc domain of the leukaemia-associated mll histone methyltransferase -1.0Å AUTH M.D.ALLEN,C.G.GRUMMITT,C.HILCENKO,S.Y.MIN,AUTH 2 L.M.TONKIN,C.M.JOHNSON,S.M.FREUND,M.BYCROFT,AUTH 3 A.J.WARRENTITL SOLUTION STRUCTURE OF THE NONMETHYL-CPG-BINDINGTITL 2 CXXC DOMAIN OF THE LEUKAEMIA-ASSOCIATED MLLTITL 3 HISTONE METHYLTRANSFERASEREF EMBO J. V. 25 4503 2006REFN ISSN 0261-4189PMID 16990798DOI 10.1038/SJ.EMBOJ.7601340 Variant Set Distributions Mapped Variants
General Structure Information 3u5o HIST1H3H crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide 2.7Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Mapped Variants