Assessment of Structural Intolerance and Durability
General Structure Information 1emo FBN1 nmr study of a pair of fibrillin ca2+ binding epidermal growth factor-like domains, 22 structures -1.0Å AUTH A.K.DOWNING,V.KNOTT,J.M.WERNER,C.M.CARDY,AUTH 2 I.D.CAMPBELL,P.A.HANDFORDTITL SOLUTION STRUCTURE OF A PAIR OF CALCIUM-BINDINGTITL 2 EPIDERMAL GROWTH FACTOR-LIKE DOMAINS: IMPLICATIONSTITL 3 FOR THE MARFAN SYNDROME AND OTHER GENETICTITL 4 DISORDERS.REF CELL(CAMBRIDGE,MASS.) V. 85 597 1996REFN ISSN 0092-8674PMID […]
General Structure Information 3cki TIMP3 crystal structure of the tace-n-timp-3 complex 2.3Å AUTH M.WISNIEWSKA,P.GOETTIG,K.MASKOS,E.BELOUSKI,AUTH 2 D.WINTERS,R.HECHT,R.BLACK,W.BODETITL STRUCTURAL DETERMINANTS OF THE ADAM INHIBITION BYTITL 2 TIMP-3: CRYSTAL STRUCTURE OF THE TACE-N-TIMP-3TITL 3 COMPLEX.REF J.MOL.BIOL. V. 381 1307 2008REFN ISSN 0022-2836PMID 18638486DOI 10.1016/J.JMB.2008.06.088 Variant Set Distributions Mapped Variants
General Structure Information 3n3f COL15A1 crystal structure of the human collagen xv trimerization domain: a potent trimerizing unit common to multiplexin collagens 2.0Å AUTH J.A.WIRZ,S.P.BOUDKO,T.F.LERCH,M.S.CHAPMAN,H.P.BACHINGERTITL CRYSTAL STRUCTURE OF THE HUMAN COLLAGEN XV TRIMERIZATIONTITL 2 DOMAIN: A POTENT TRIMERIZING UNIT COMMON TO MULTIPLEXINTITL 3 COLLAGENS.REF MATRIX BIOL. V. 30 9 2011REFN ISSN 0945-053XPMID 20932905DOI 10.1016/J.MATBIO.2010.09.005 Variant […]
General Structure Information 1bnl COL18A1 zinc dependent dimers observed in crystals of human endostatin 2.9Å AUTH Y.H.DING,K.JAVAHERIAN,K.M.LO,R.CHOPRA,T.BOEHM,AUTH 2 J.LANCIOTTI,B.A.HARRIS,Y.LI,R.SHAPIRO,E.HOHENESTER,AUTH 3 R.TIMPL,J.FOLKMAN,D.C.WILEYTITL ZINC-DEPENDENT DIMERS OBSERVED IN CRYSTALS OFTITL 2 HUMAN ENDOSTATIN.REF PROC.NATL.ACAD.SCI.USA V. 95 10443 1998REFN ISSN 0027-8424PMID 9724722DOI 10.1073/PNAS.95.18.10443 Variant Set Distributions Mapped Variants
General Structure Information 2uur COL9A1 n-terminal nc4 domain of collagen ix 1.8Å AUTH V.-M.LEPPANEN,H.TOSSAVAINEN,P.PERMI,L.LEHTIO,AUTH 2 G.RONNHOLM,A.GOLDMAN,I.KILPELAINEN,T.PIHLAJAMAATITL CRYSTAL STRUCTURE OF THE N-TERMINAL NC4 DOMAIN OFTITL 2 COLLAGEN IX, A ZINC BINDING MEMBER OF THE LAMININ-TITL 3 NEUREXIN-SEX HORMONE BINDING GLOBULIN (LNS) DOMAINTITL 4 FAMILY.REF J.BIOL.CHEM. V. 282 23219 2007REFN ISSN 0021-9258PMID 17553797DOI 10.1074/JBC.M702514200 Variant Set Distributions […]
General Structure Information 2rbl TNC high resolution design of a protein loop 2.1Å AUTH X.HU,H.WANG,H.KE,B.KUHLMANTITL HIGH-RESOLUTION DESIGN OF A PROTEIN LOOP.REF PROC.NATL.ACAD.SCI.USA V. 104 17668 2007REFN ISSN 0027-8424PMID 17971437DOI 10.1073/PNAS.0707977104 Variant Set Distributions Mapped Variants
General Structure Information 4aej COL3A1 crystal structure of human fibrillar procollagen type iii c- propeptide trimer 2.21Å AUTH J.M.BOURHIS,N.MARIANO,Y.ZHAO,K.HARLOS,J.EXPOSITO,E.Y.JONES,AUTH 2 C.MOALI,N.AGHAJARI,D.J.S.HULMESTITL STRUCTURAL BASIS OF FIBRILLAR COLLAGEN TRIMERIZATION ANDTITL 2 RELATED GENETIC DISORDERS.REF NAT.STRUCT.MOL.BIOL. V. 19 1031 2012REFN ISSN 1545-9993PMID 23001006DOI 10.1038/NSMB.2389 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants