Assessment of Structural Intolerance and Durability
General Structure Information 3ebb PLAA plap/p97 complex 1.9Å AUTH L.QIU,N.PASHKOVA,J.R.WALKER,S.WINISTORFER,A.ALLALI-HASSANI,AUTH 2 M.AKUTSU,R.PIPER,S.DHE-PAGANONTITL STRUCTURE AND FUNCTION OF THE PLAA/UFD3-P97/CDC48 COMPLEX.REF J.BIOL.CHEM. V. 285 365 2010REFN ISSN 0021-9258PMID 19887378DOI 10.1074/JBC.M109.044685 Variant Set Distributions Mapped Variants
General Structure Information 2v8s VTI1B vti1b habc domain – epsinr enth domain complex 2.22Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN COATED VESICLESREF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 2r55 STARD5 human star-related lipid transfer protein 5 2.5Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Mapped Variants
General Structure Information 1eaz PLEKHA1 crystal structure of the phosphoinositol (3,4)-bisphosphate binding ph domain of tapp1 from human. 1.4Å AUTH C.C.THOMAS,S.DOWLER,M.DEAK,D.R.ALESSI,AUTH 2 D.M.F.VAN AALTENTITL CRYSTAL STRUCTURE OF THE PHOSPHATIDYLINOSITOLTITL 2 3,4-BISPHOSPHATE-BINDING PLECKSTRIN HOMOLOGY (PH)TITL 3 DOMAIN OF TANDEM PH-DOMAIN-CONTAINING PROTEIN 1TITL 4 (TAPP1): MOLECULAR BASIS OF LIPID SPECIFICITYREF BIOCHEM.J. V. 358 287 2001REFN ISSN 0264-6021PMID […]
General Structure Information 4aiw GLIPR2 gapr-1 with bound inositol hexakisphosphate 1.5Å AUTH J.VAN GALEN,N.K.OLRICHS,A.SCHOUTEN,R.L.SERRANO,AUTH 2 E.N.M.NOLTE-T HOEN,R.EERLAND,D.KALOYANOVA,P.GROS,J.B.HELMSTITL INTERACTION OF GAPR-1 WITH LIPID BILAYERS IS REGULATED BYTITL 2 ALTERNATIVE HOMODIMERIZATION.REF BIOCHIM.BIOPHYS.ACTA V.1818 2175 2012REFN ISSN 0006-3002PMID 22560898DOI 10.1016/J.BBAMEM.2012.04.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3cuq VPS25 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 2zme SNF8 integrated structural and functional model of the human escrt-ii complex 2.9Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 3cuq VPS36 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 2qy7 CLINT1 crystal structure of human epsinr enth domain 2.0Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN-COATED VESICLES.REF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 2ke4 TRIP10 the nmr structure of the tc10 and cdc42 interacting domain of cip4 -1.0Å AUTH Y.KOBASHIGAWA,H.KUMETA,D.KANOH,F.INAGAKITITL THE NMR STRUCTURE OF THE TC10- ANDTITL 2 CDC42-INTERACTING DOMAIN OF CIP4.REF J.BIOMOL.NMR V. 44 113 2009REFN ISSN 0925-2738PMID 19387844DOI 10.1007/S10858-009-9317-Z Variant Set Distributions Mapped Variants