Assessment of Structural Intolerance and Durability
General Structure Information 2pvy FGFR2 crystal strucure of fgf receptor 2 (fgfr2) kinase domain harboring the pathogenic k659n mutation responsible for an unclassified craniosynostosis syndrome. 2.2Å AUTH H.CHEN,J.MA,W.LI,A.V.ELISEENKOVA,C.XU,T.A.NEUBERT,AUTH 2 W.T.MILLER,M.MOHAMMADITITL A MOLECULAR BRAKE IN THE KINASE HINGE REGION REGULATES THETITL 2 ACTIVITY OF RECEPTOR TYROSINE KINASES.REF MOL.CELL V. 27 717 2007REFN ISSN 1097-2765PMID 17803937DOI 10.1016/J.MOLCEL.2007.06.028 […]
General Structure Information 4k33 FGFR3 crystal strucure of fgf receptor 3 (fgfr3) kinase domain harboring the k650e mutation, a gain-of-function mutation responsible for thanatophoric dysplasia type ii and spermatocytic seminoma 2.34Å AUTH Z.HUANG,H.CHEN,S.BLAIS,T.A.NEUBERT,X.LI,M.MOHAMMADITITL STRUCTURAL MIMICRY OF A-LOOP TYROSINE PHOSPHORYLATION BY ATITL 2 PATHOGENIC FGF RECEPTOR 3 MUTATION.REF STRUCTURE V. 21 1889 2013REFN ISSN 0969-2126PMID 23972473DOI […]