General Structure Information 2kav SCN2A solution structure of the human voltage-gated sodium channel, brain isoform (nav1.2) -1.0Å AUTH V.Z.MILOUSHEV,J.A.LEVINE,M.A.ARBING,J.F.HUNT,G.S.PITT,AUTH 2 A.G.PALMERTITL SOLUTION STRUCTURE OF THE NAV1.2 C-TERMINAL EF-HAND DOMAIN.REF J.BIOL.CHEM. V. 284 6446 2009REFN ISSN 0021-9258PMID 19129176DOI 10.1074/JBC.M807401200 Variant Set Distributions Mapped Variants
General Structure Information 3a2a HVCN1 the structure of the carboxyl-terminal domain of the human voltage- gated proton channel hv1 2.0Å AUTH S.J.LI,Q.ZHAO,Q.ZHOU,H.UNNO,Y.ZHAI,F.SUNTITL THE ROLE AND STRUCTURE OF THE CARBOXYL-TERMINAL DOMAIN OFTITL 2 THE HUMAN VOLTAGE-GATED PROTON CHANNEL HV1.REF J.BIOL.CHEM. V. 285 12047 2010REFN ISSN 0021-9258PMID 20147290DOI 10.1074/JBC.M109.040360 Variant Set Distributions Mapped Variants
General Structure Information 2kle PKD2 isic refined solution structure of the calcium binding domain of the c-terminal cytosolic domain of polycystin-2 -1.0Å AUTH F.H.SCHUMANN,H.HOFFMEISTER,M.SCHMIDT,R.BADER,AUTH 2 E.BESL,R.WITZGALL,H.R.KALBITZERTITL NMR-ASSIGNMENTS OF A CYTOSOLIC DOMAIN OF THETITL 2 C-TERMINUS OF POLYCYSTIN-2REF BIOMOL.NMR ASSIGN. V. 3 141 2009REFN ISSN 1874-2718PMID 19636966DOI 10.1007/S12104-009-9160-X Variant Set Distributions Mapped Variants
General Structure Information 3hrn PKD2 crystal structure of a c-terminal coiled coil domain of transient receptor potential (trp) channel subfamily p member 2 (trpp2, polycystic kidney disease 2) 1.9Å AUTH Y.YU,M.H.ULBRICH,M.H.LI,Z.BURAEI,X.Z.CHEN,A.C.ONG,AUTH 2 L.TONG,E.Y.ISACOFF,J.YANGTITL STRUCTURAL AND MOLECULAR BASIS OF THE ASSEMBLY OFTITL 2 THE TRPP2/PKD1 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 106 11558 2009REFN ISSN 0027-8424PMID 19556541DOI 10.1073/PNAS.0903684106 Variant […]
General Structure Information 2ja3 CLCN5 cytoplasmic domain of the human chloride transporter clc-5 in complex with adp 3.05Å AUTH S.MEYER,S.SAVARESI,I.C.FORSTER,R.DUTZLERTITL NUCLEOTIDE RECOGNITION BY THE CYTOPLASMIC DOMAINTITL 2 OF THE HUMAN CHLORIDE TRANSPORTER CLC-5REF NAT.STRUCT.MOL.BIOL. V. 14 60 2006REFN ISSN 1545-9993PMID 17195847DOI 10.1038/NSMB1188 Variant Set Distributions Mapped Variants
General Structure Information 3ua8 GRIA2 crystal structure analysis of a 6-amino quinazolinedione sulfonamide bound to human glur2 1.9Å AUTH D.ORAIN,S.OFNER,M.KOLLER,D.A.CARCACHE,W.FROESTL,H.ALLGEIER,AUTH 2 V.RASETTI,J.NOZULAK,H.MATTES,N.SOLDERMANN,P.FLOERSHEIM,AUTH 3 S.DESRAYAUD,J.KALLEN,K.LINGENHOEHL,S.URWYLERTITL 6-AMINO QUINAZOLINEDIONE SULFONAMIDES AS ORALLY ACTIVETITL 2 COMPETITIVE AMPA RECEPTOR ANTAGONISTS.REF BIOORG.MED.CHEM.LETT. V. 22 996 2012REFN ISSN 0960-894XPMID 22197388DOI 10.1016/J.BMCL.2011.12.009 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2wjx GRIA2 crystal structure of the human ionotropic glutamate receptor glur2 atd region at 4.1 a resolution 4.1Å AUTH A.CLAYTON,C.SIEBOLD,R.J.C.GILBERT,G.C.SUTTON,AUTH 2 K.HARLOS,R.A.J.MCILHINNEY,E.Y.JONES,A.R.ARICESCUTITL CRYSTAL STRUCTURE OF THE GLUR2 AMINO-TERMINALTITL 2 DOMAIN PROVIDES INSIGHTS INTO THE ARCHITECTURE ANDTITL 3 ASSEMBLY OF IONOTROPIC GLUTAMATE RECEPTORS.REF J.MOL.BIOL. V. 392 1125 2009REFN ISSN 0022-2836PMID 19651138DOI 10.1016/J.JMB.2009.07.082 Variant […]
General Structure Information 2zns GRIK1 crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, glur5, in complex with glutamate 2.0Å AUTH M.UNNO,M.SHINOHARA,K.TAKAYAMA,H.TANAKA,K.TERUYA,K.DOH-URA,AUTH 2 R.SAKAI,M.SASAKI,M.IKEDA-SAITOTITL BINDING AND SELECTIVITY OF THE MARINE TOXIN NEODYSIHERBAINETITL 2 A AND ITS SYNTHETIC ANALOGUES TO GLUK1 AND GLUK2 KAINATETITL 3 RECEPTORS.REF J.MOL.BIOL. V. 413 667 2011REFN ISSN 0022-2836PMID […]