Assessment of Structural Intolerance and Durability
General Structure Information 1afo GYPA dimeric transmembrane domain of human glycophorin a, nmr, 20 structures -1.0Å AUTH K.R.MACKENZIE,J.H.PRESTEGARD,D.M.ENGELMANTITL A TRANSMEMBRANE HELIX DIMER: STRUCTURE ANDTITL 2 IMPLICATIONS.REF SCIENCE V. 276 131 1997REFN ISSN 0036-8075PMID 9082985DOI 10.1126/SCIENCE.276.5309.131 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4aw6 ZMPSTE24 crystal structure of the human nuclear membrane zinc metalloprotease zmpste24 (face1) 3.4Å AUTH A.QUIGLEY,Y.Y.DONG,A.C.W.PIKE,L.DONG,L.SHRESTHA,G.BERRIDGE,AUTH 2 P.J.STANSFELD,M.S.P.SANSOM,A.M.EDWARDS,C.BOUNTRA,AUTH 3 F.VON DELFT,A.N.BULLOCK,N.A.BURGESS-BROWN,E.P.CARPENTERTITL THE STRUCTURAL BASIS OF ZMPSTE24-DEPENDENT LAMINOPATHIES.REF SCIENCE V. 339 1604 2013REFN ISSN 0036-8075PMID 23539603DOI 10.1126/SCIENCE.1231513 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants