General Structure Information 2shp PTPN11 tyrosine phosphatase shp-2 2.0Å AUTH P.HOF,S.PLUSKEY,S.DHE-PAGANON,M.J.ECK,S.E.SHOELSONTITL CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASETITL 2 SHP-2.REF CELL(CAMBRIDGE,MASS.) V. 92 441 1998REFN ISSN 0092-8674PMID 9491886DOI 10.1016/S0092-8674(00)80938-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2shp PTPN11 tyrosine phosphatase shp-2 2.0Å AUTH P.HOF,S.PLUSKEY,S.DHE-PAGANON,M.J.ECK,S.E.SHOELSONTITL CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASETITL 2 SHP-2.REF CELL(CAMBRIDGE,MASS.) V. 92 441 1998REFN ISSN 0092-8674PMID 9491886DOI 10.1016/S0092-8674(00)80938-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dsr IGFBP4 structural basis for the inhibition of insulin-like growth factors by igf binding proteins 2.1Å AUTH T.SITAR,G.M.POPOWICZ,I.SIWANOWICZ,R.HUBER,T.A.HOLAKTITL STRUCTURAL BASIS FOR THE INHIBITION OFTITL 2 INSULIN-LIKE GROWTH FACTORS BY INSULIN-LIKE GROWTHTITL 3 FACTOR-BINDING PROTEINS.REF PROC.NATL.ACAD.SCI.USA V. 103 13028 2006REFN ISSN 0027-8424PMID 16924115DOI 10.1073/PNAS.0605652103 Variant Set Distributions Mapped Variants
General Structure Information 3w14 INSR insulin receptor ectodomain construct comprising domains l1,cr,l2, fniii-1 and alphact peptide in complex with bovine insulin and fab 83-14 4.4Å AUTH J.G.MENTING,J.WHITTAKER,M.B.MARGETTS,L.J.WHITTAKER,AUTH 2 G.K.-W.KONG,B.J.SMITH,C.J.WATSON,L.ZAKOVA,E.KLETVIKOVA,AUTH 3 J.JIRACEK,S.J.CHAN,D.F.STEINER,G.G.DODSON,A.M.BRZOZOWSKI,AUTH 4 M.A.WEISS,C.W.WARD,M.C.LAWRENCETITL HOW INSULIN ENGAGES ITS PRIMARY BINDING SITE ON THE INSULINTITL 2 RECEPTORREF NATURE V. 493 241 2013REFN ISSN 0028-0836PMID 23302862DOI 10.1038/NATURE11781 Variant […]