Assessment of Structural Intolerance and Durability
General Structure Information 3bu6 INSR crystal structure of the insulin receptor kinase in complex with irs2 krlb phosphopeptide 1.95Å AUTH J.WU,Y.D.TSENG,C.F.XU,T.A.NEUBERT,M.F.WHITE,AUTH 2 S.R.HUBBARDTITL STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF THETITL 2 KRLB REGION IN INSULIN RECEPTOR SUBSTRATE-2.REF NAT.STRUCT.MOL.BIOL. V. 15 251 2008REFN ISSN 1545-9993PMID 18278056DOI 10.1038/NSMB.1388 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3w14 INSR insulin receptor ectodomain construct comprising domains l1,cr,l2, fniii-1 and alphact peptide in complex with bovine insulin and fab 83-14 4.4Å AUTH J.G.MENTING,J.WHITTAKER,M.B.MARGETTS,L.J.WHITTAKER,AUTH 2 G.K.-W.KONG,B.J.SMITH,C.J.WATSON,L.ZAKOVA,E.KLETVIKOVA,AUTH 3 J.JIRACEK,S.J.CHAN,D.F.STEINER,G.G.DODSON,A.M.BRZOZOWSKI,AUTH 4 M.A.WEISS,C.W.WARD,M.C.LAWRENCETITL HOW INSULIN ENGAGES ITS PRIMARY BINDING SITE ON THE INSULINTITL 2 RECEPTORREF NATURE V. 493 241 2013REFN ISSN 0028-0836PMID 23302862DOI 10.1038/NATURE11781 Variant […]