Assessment of Structural Intolerance and Durability
General Structure Information 3qfv CDC42BPB mrck beta in complex with tpca-1 2.65Å AUTH T.HEIKKILA,E.WHEATLEY,D.CRIGHTON,E.SCHRODER,A.BOAKES,AUTH 2 S.J.KAYE,M.MEZNA,L.PANG,M.RUSHBROOKE,A.TURNBULL,M.F.OLSONTITL CO-CRYSTAL STRUCTURES OF INHIBITORS WITH MRCK BETA , A KEYTITL 2 REGULATOR OF TUMOR CELL INVASION.REF PLOS ONE V. 6 24825 2011REFN ESSN 1932-6203PMID 21949762DOI 10.1371/JOURNAL.PONE.0024825 Variant Set Distributions Mapped Variants
General Structure Information 2eo9 ROBO1 solution structure of the fifth ig-like domain from human roundabout homo1 -1.0Å AUTH K.NAGASHIMA,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAINTITL 2 FROM HUMAN ROUNDABOUT HOMO1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1rl1 SUGT1 solution structure of human sgt1 cs domain -1.0Å AUTH Y.-T.LEE,J.JACOB,W.MICHOWSKI,M.NOWOTNY,J.KUZNICKI,AUTH 2 W.J.CHAZINTITL HUMAN SGT1 BINDS HSP90 THROUGH THE CHORD-SGT1TITL 2 DOMAIN AND NOT THE TETRATRICOPEPTIDE REPEAT DOMAINREF J.BIOL.CHEM. V. 279 16511 2004REFN ISSN 0021-9258PMID 14761955DOI 10.1074/JBC.M400215200 Variant Set Distributions Mapped Variants
General Structure Information 3t9l USP15 structure of n-terminal dusp-ubl domains of human usp15 1.5Å AUTH S.HARPER,T.M.BESONG,J.EMSLEY,D.J.SCOTT,I.DREVENYTITL STRUCTURE OF THE USP15 N-TERMINAL DOMAINS: A BETA-HAIRPINTITL 2 MEDIATES CLOSE ASSOCIATION BETWEEN THE DUSP AND UBL DOMAINSREF BIOCHEMISTRY V. 50 7995 2011REFN ISSN 0006-2960PMID 21848306DOI 10.1021/BI200726E Variant Set Distributions Mapped Variants
General Structure Information 2b1u CALML5 solution structure of calmodulin-like skin protein c terminal domain -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,E.CHIRIVINO,C.LUCHINATTITL A STRUCTURAL AND DYNAMIC CHARACTERIZATION OF THETITL 2 EF-HAND PROTEIN CLSP.REF STRUCTURE V. 14 1029 2006REFN ISSN 0969-2126PMID 16765896DOI 10.1016/J.STR.2006.04.004 Variant Set Distributions Mapped Variants
General Structure Information 2ell ANP32B solution structure of the leucine rich repeat of human acidic leucine- rich nuclear phosphoprotein 32 family member b -1.0Å AUTH N.TOCHIO,T.UMEHARA,Y.MUNEMASA,T.SUZUKI,S.SATO,K.TSUDA,AUTH 2 S.KOSHIBA,T.KIGAWA,R.NAGAI,S.YOKOYAMATITL SOLUTION STRUCTURE OF HISTONE CHAPERONE ANP32B: INTERACTIONTITL 2 WITH CORE HISTONES H3-H4 THROUGH ITS ACIDIC CONCAVE DOMAIN.REF J.MOL.BIOL. V. 401 97 2010REFN ISSN 0022-2836PMID 20538007DOI 10.1016/J.JMB.2010.06.005 Variant […]
General Structure Information 3c9q WDYHV1 crystal structure of the uncharacterized human protein c8orf32 with bound peptide 1.5Å AUTH E.BITTO,C.A.BINGMAN,J.G.MCCOY,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE UNCHARACTERIZED HUMAN PROTEINTITL 2 C8ORF32 WITH BOUND PEPTIDE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2rkb SDSL serine dehydratase like-1 from human cancer cells 2.8Å AUTH T.YAMADA,J.KOMOTO,T.KASUYA,Y.TAKATA,H.OGAWA,H.MORI,AUTH 2 F.TAKUSAGAWATITL A CATALYTIC MECHANISM THAT EXPLAINS A LOW CATALYTIC ACTIVITYTITL 2 OF SERINE DEHYDRATASE LIKE-1 FROM HUMAN CANCER CELLS:TITL 3 CRYSTAL STRUCTURE AND SITE-DIRECTED MUTAGENESIS STUDIES.REF BIOCHIM.BIOPHYS.ACTA V.1780 809 2008REFN ISSN 0006-3002PMID 18342636DOI 10.1016/J.BBAGEN.2008.01.020 Variant Set Distributions Ripley’s K […]
General Structure Information 1olz SEMA4D the ligand-binding face of the semaphorins revealed by the high resolution crystal structure of sema4d 2.0Å AUTH C.A.LOVE,K.HARLOS,N.MAVADDAT,S.J.DAVIS,D.I.STUART,AUTH 2 E.Y.JONES,R.M.ESNOUFTITL THE LIGAND-BINDING FACE OF THE SEMAPHORINSTITL 2 REVEALED BY THE HIGH-RESOLUTION CRYSTAL STRUCTURETITL 3 OF SEMA4DREF NAT.STRUCT.BIOL. V. 10 843 2003REFN ISSN 1072-8368PMID 12958590DOI 10.1038/NSB977 Variant Set Distributions Ripley’s K […]
General Structure Information 1y3j ATP7A solution structure of the copper(i) form of the fifth domain of menkes protein -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,C.T.CHASAPIS,AUTH 2 N.HADJILIADIS,A.ROSATOTITL AN NMR STUDY OF THE INTERACTION BETWEEN THE HUMANTITL 2 COPPER(I) CHAPERONE AND THE SECOND AND FIFTHTITL 3 METAL-BINDING DOMAINS OF THE MENKES PROTEINREF FEBS J. V. 272 865 2005REFN ISSN 1742-464XPMID […]