Assessment of Structural Intolerance and Durability
General Structure Information 3h6a ITGB4 structure of the calx-beta domain of integrin beta4 crystallized in the presence of calcium 1.61Å AUTH N.ALONSO-GARCIA,A.INGLES-PRIETO,A.SONNENBERG,AUTH 2 J.M.DE PEREDATITL STRUCTURE OF THE CALX-BETA DOMAIN OF THE INTEGRINTITL 2 BETA4 SUBUNIT: INSIGHTS INTO FUNCTION ANDTITL 3 CATION-INDEPENDENT STABILITYREF ACTA CRYSTALLOGR.,SECT.D V. 65 858 2009REFN ISSN 0907-4449PMID 19622870DOI 10.1107/S0907444909018745 Variant Set […]
General Structure Information 1itb IL1R1 type-1 interleukin-1 receptor complexed with interleukin-1 beta 2.5Å AUTH G.P.VIGERS,L.J.ANDERSON,P.CAFFES,B.J.BRANDHUBERTITL CRYSTAL STRUCTURE OF THE TYPE-I INTERLEUKIN-1TITL 2 RECEPTOR COMPLEXED WITH INTERLEUKIN-1BETA.REF NATURE V. 386 190 1997REFN ISSN 0028-0836PMID 9062193DOI 10.1038/386190A0 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1zxq ICAM2 the crystal structure of icam-2 2.2Å AUTH J.M.CASASNOVAS,T.A.SPRINGER,J.H.LIU,S.C.HARRISON,J.H.WANGTITL CRYSTAL STRUCTURE OF ICAM-2 REVEALS A DISTINCTIVE INTEGRINTITL 2 RECOGNITION SURFACE.REF NATURE V. 387 312 1997REFN ISSN 0028-0836PMID 9153399DOI 10.1038/387312A0 Variant Set Distributions Mapped Variants
General Structure Information 1wio CD4 structure of t-cell surface glycoprotein cd4, tetragonal crystal form 3.9Å AUTH H.WU,P.D.KWONG,W.A.HENDRICKSONTITL DIMERIC ASSOCIATION AND SEGMENTAL VARIABILITY IN THETITL 2 STRUCTURE OF HUMAN CD4.REF NATURE V. 387 527 1997REFN ISSN 0028-0836PMID 9168119DOI 10.1038/387527A0 Variant Set Distributions Mapped Variants
General Structure Information 1xiw CD3D crystal structure of human cd3-e/d dimer in complex with a ucht1 single-chain antibody fragment 1.9Å AUTH K.L.ARNETT,S.C.HARRISON,D.C.WILEYTITL CRYSTAL STRUCTURE OF A HUMAN CD3-EPSILON/DELTATITL 2 DIMER IN COMPLEX WITH A UCHT1 SINGLE-CHAINTITL 3 ANTIBODY FRAGMENT.REF PROC.NATL.ACAD.SCI.USA V. 101 16268 2004REFN ISSN 0027-8424PMID 15534202DOI 10.1073/PNAS.0407359101 Variant Set Distributions Mapped Variants