General Structure Information 1f3m PAK1 crystal structure of human serine/threonine kinase pak1 2.3Å AUTH M.LEI,W.LU,W.MENG,M.C.PARRINI,M.J.ECK,B.J.MAYER,AUTH 2 S.C.HARRISONTITL STRUCTURE OF PAK1 IN AN AUTOINHIBITED CONFORMATIONTITL 2 REVEALS A MULTISTAGE ACTIVATION SWITCH.REF CELL(CAMBRIDGE,MASS.) V. 102 387 2000REFN ISSN 0092-8674PMID 10975528DOI 10.1016/S0092-8674(00)00043-X Variant Set Distributions Mapped Variants
General Structure Information 2j5d BNIP3 nmr structure of bnip3 transmembrane domain in lipid bicelles -1.0Å AUTH E.V.BOCHAROV,Y.E.PUSTOVALOVA,K.V.PAVLOV,AUTH 2 P.E.VOLYNSKY,M.V.GONCHARUK,Y.S.ERMOLYUK,AUTH 3 D.V.KARPUNIN,A.A.SCHULGA,M.P.KIRPICHNIKOV,AUTH 4 R.G.EFREMOV,I.V.MASLENNIKOV,A.S.ARSENIEVTITL UNIQUE DIMERIC STRUCTURE OF BNIP3 TRANSMEMBRANETITL 2 DOMAIN SUGGESTS MEMBRANE PERMEABILIZATION AS ATITL 3 CELL DEATH TRIGGER.REF J.BIOL.CHEM. V. 282 16256 2007REFN ISSN 0021-9258PMID 17412696DOI 10.1074/JBC.M701745200 Variant Set Distributions Mapped Variants
General Structure Information 4gtu GSTM4 ligand-free homodimeric human glutathione s-transferase m4-4 3.3Å AUTH Y.V.PATSKOVSKY,L.N.PATSKOVSKA,I.LISTOWSKYTITL AN ASPARAGINE-PHENYLALANINE SUBSTITUTION ACCOUNTS FORTITL 2 CATALYTIC DIFFERENCES BETWEEN HGSTM3-3 AND OTHER HUMAN CLASSTITL 3 MU GLUTATHIONE S-TRANSFERASES.REF BIOCHEMISTRY V. 38 16187 1999REFN ISSN 0006-2960PMID 10587441DOI 10.1021/BI991714T Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2kyg RUNX1T1 structure of the aml1-eto nervy domain – pka(riia) complex and its contribution to aml1-eto activity -1.0Å AUTH T.CORPORA,L.ROUDAIA,Z.M.OO,W.CHEN,E.MANUYLOVA,X.CAI,AUTH 2 M.J.CHEN,T.CIERPICKI,N.A.SPECK,J.H.BUSHWELLERTITL STRUCTURE OF THE AML1-ETO NHR3-PKA(RIIALPHA) COMPLEX AND ITSTITL 2 CONTRIBUTION TO AML1-ETO ACTIVITY.REF J.MOL.BIOL. V. 402 560 2010REFN ISSN 0022-2836PMID 20708017DOI 10.1016/J.JMB.2010.08.007 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2luc S100A11 solution structure of human s100 calcium-binding protein a11 -1.0Å AUTH K.W.HUNG,Y.M.CHANG,C.YUTITL NMR STRUCTURE NOTE: THE STRUCTURE OF HUMAN CALCIUM-BOUNDTITL 2 S100A11.REF J.BIOMOL.NMR V. 54 211 2012REFN ISSN 0925-2738PMID 22903637DOI 10.1007/S10858-012-9661-2 Variant Set Distributions Mapped Variants
General Structure Information 2fi2 MZF1 solution structure of the scan homodimer from mzf-1/znf42 -1.0Å AUTH F.C.PETERSON,P.L.HAYES,J.K.WALTNER,A.K.HEISNER,AUTH 2 D.R.JENSEN,T.L.SANDER,B.F.VOLKMANTITL STRUCTURE OF THE SCAN DOMAIN FROM THE TUMORTITL 2 SUPPRESSOR PROTEIN MZF1.REF J.MOL.BIOL. V. 363 137 2006REFN ISSN 0022-2836PMID 16950398DOI 10.1016/J.JMB.2006.07.063 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3cnk FLNA crystal structure of the dimerization domain of human filamin a 1.65Å AUTH M.-D.SEO,S.-H.SEOK,H.IM,A.-R.KWON,S.-J.LEE,AUTH 2 H.-R.KIM,Y.CHO,D.PARK,B.-J.LEETITL CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAIN OFTITL 2 HUMAN FILAMIN AREF PROTEINS V. 75 258 2008REFN ISSN 0887-3585PMID 19137608DOI 10.1002/PROT.22336 Variant Set Distributions Mapped Variants
General Structure Information 1don CCL2 solution structure of the monocyte chemoattractant protein- 1 dimer using heteronuclear, nmr, 20 structures -1.0Å AUTH T.M.HANDEL,P.J.DOMAILLETITL HETERONUCLEAR (1H, 13C, 15N) NMR ASSIGNMENTS ANDTITL 2 SOLUTION STRUCTURE OF THE MONOCYTE CHEMOATTRACTANTTITL 3 PROTEIN-1 (MCP-1) DIMER.REF BIOCHEMISTRY V. 35 6569 1996REFN ISSN 0006-2960PMID 8639605DOI 10.1021/BI9602270 Variant Set Distributions Mapped Variants
General Structure Information 2arv INHBA structure of human activin a 2.0Å AUTH A.E.HARRINGTON,S.A.MORRIS-TRIGGS,B.T.RUOTOLO,C.V.ROBINSON,AUTH 2 S.OHNUMA,M.HYVONENTITL STRUCTURAL BASIS FOR THE INHIBITION OF ACTIVIN SIGNALLING BYTITL 2 FOLLISTATINREF EMBO J. V. 25 1035 2006REFN ISSN 0261-4189PMID 16482217DOI 10.1038/SJ.EMBOJ.7601000 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2fic BIN1 the crystal structure of the bar domain from human bin1/amphiphysin ii and its implications for molecular recognition 1.99Å AUTH E.CASAL,L.FEDERICI,W.ZHANG,J.FERNANDEZ-RECIO,E.M.PRIEGO,AUTH 2 R.N.MIGUEL,J.B.DUHADAWAY,G.C.PRENDERGAST,B.F.LUISI,E.D.LAUETITL THE CRYSTAL STRUCTURE OF THE BAR DOMAIN FROM HUMANTITL 2 BIN1/AMPHIPHYSIN II AND ITS IMPLICATIONS FOR MOLECULARTITL 3 RECOGNITIONREF BIOCHEMISTRY V. 45 12917 2006REFN ISSN 0006-2960PMID 17059209DOI 10.1021/BI060717K […]