Assessment of Structural Intolerance and Durability
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1q9c SOS1 crystal structure of the histone domain of son of sevenless 3.21Å AUTH H.SONDERMANN,S.M.SOISSON,D.BAR-SAGI,J.KURIYANTITL TANDEM HISTONE FOLDS IN THE STRUCTURE OF THETITL 2 N-TERMINAL SEGMENT OF THE RAS ACTIVATOR SON OFTITL 3 SEVENLESSREF STRUCTURE V. 11 1583 2003REFN ISSN 0969-2126PMID 14656442DOI 10.1016/J.STR.2003.10.015 Variant Set Distributions Mapped Variants
General Structure Information 4bkx MTA1 the structure of hdac1 in complex with the dimeric elm2-sant domain of mta1 from the nurd complex 3.0Å AUTH C.J.MILLARD,P.J.WATSON,I.CELARDO,Y.GORDIYENKO,S.M.COWLEY,AUTH 2 C.V.ROBINSON,L.FAIRALL,J.W.R.SCHWABETITL CLASS I HDACS SHARE A COMMON MECHANISM OF REGULATION BYTITL 2 INOSITOL PHOSPHATES.REF MOL.CELL V. 51 57 2013REFN ISSN 1097-2765PMID 23791785DOI 10.1016/J.MOLCEL.2013.05.020 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2xu7 RBBP4 structural basis for rbap48 binding to fog-1 1.9Å AUTH S.LEJON,S.Y.THONG,A.MURTHY,S.ALQARNI,N.V.MURZINA,G.A.BLOBEL,AUTH 2 E.D.LAUE,J.P.MACKAYTITL INSIGHTS INTO ASSOCIATION OF THE NURD COMPLEX WITH FOG-1TITL 2 FROM THE CRYSTAL STRUCTURE OF AN RBAP48-FOG- 1 COMPLEX.REF J.BIOL.CHEM. V. 286 1196 2011REFN ISSN 0021-9258PMID 21047798DOI 10.1074/JBC.M110.195842 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]