Assessment of Structural Intolerance and Durability
General Structure Information 2cto MAEL solution structure of the hmg box like domain from human hypothetical protein flj14904 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 Y.O.KAMATARI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX LIKE DOMAIN FROMTITL 2 HUMAN HYPOTHETICAL PROTEIN FLJ14904REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2khn ITSN1 nmr solution structure of the eh 1 domain from human intersectin-1 protein. northeast structural genomics consortium target hr3646e. -1.0Å AUTH J.L.MILLS,A.GHOSH,E.GARCIA,Q.ZHANG,R.SHASTRY,AUTH 2 E.L.FOOTE,H.JANJUA,T.B.ACTON,R.XIAO,J.K.EVERETT,AUTH 3 G.T.MONTELIONE,T.SZYPERSKITITL NMR SOLUTION STRUCTURE OF THE EH 1 DOMAIN FROMTITL 2 HUMAN INTERSECTIN-1 PROTEIN. NORTHEAST STRUCTURALTITL 3 GENOMICS CONSORTIUM TARGET HR3646E.REF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 3kb5 TRIM72 pry-spry domain of human trim72 1.5Å AUTH E.Y.PARK,O.-B.KWON,B.-C.JEONG,J.-S.YI,C.S.LEE,AUTH 2 Y.-G.KO,H.K.SONGTITL CRYSTAL STRUCTURE OF PRY-SPRY DOMAIN OF HUMANTITL 2 TRIM72REF PROTEINS 2009REFN ESSN 1097-0134PMID 19967786DOI 10.1002/PROT.22647 Variant Set Distributions Mapped Variants
General Structure Information 2h2b TJP1 crystal structure of zo-1 pdz1 bound to a phage-derived ligand (wrrttyl) 1.6Å AUTH B.A.APPLETON,Y.ZHANG,P.WU,J.P.YIN,W.HUNZIKER,N.J.SKELTON,AUTH 2 S.S.SIDHU,C.WIESMANNTITL COMPARATIVE STRUCTURAL ANALYSIS OF THE ERBIN PDZ DOMAIN ANDTITL 2 THE FIRST PDZ DOMAIN OF ZO-1. INSIGHTS INTO DETERMINANTS OFTITL 3 PDZ DOMAIN SPECIFICITY.REF J.BIOL.CHEM. V. 281 22312 2006REFN ISSN 0021-9258PMID 16737969DOI 10.1074/JBC.M602901200 Variant […]
General Structure Information 2p3w HTRA3 crystal structure of the htra3 pdz domain bound to a phage-derived ligand (fgrwv) 1.7Å AUTH S.T.RUNYON,Y.ZHANG,B.A.APPLETON,S.L.SAZINSKY,P.WU,B.PAN,AUTH 2 C.WIESMANN,N.J.SKELTON,S.S.SIDHUTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PDZ DOMAINS OFTITL 2 HUMAN HTRA1 AND HTRA3.REF PROTEIN SCI. V. 16 2454 2007REFN ISSN 0961-8368PMID 17962403DOI 10.1110/PS.073049407 Variant Set Distributions Mapped Variants
General Structure Information 2p3w HTRA3 crystal structure of the htra3 pdz domain bound to a phage-derived ligand (fgrwv) 1.7Å AUTH S.T.RUNYON,Y.ZHANG,B.A.APPLETON,S.L.SAZINSKY,P.WU,B.PAN,AUTH 2 C.WIESMANN,N.J.SKELTON,S.S.SIDHUTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PDZ DOMAINS OFTITL 2 HUMAN HTRA1 AND HTRA3.REF PROTEIN SCI. V. 16 2454 2007REFN ISSN 0961-8368PMID 17962403DOI 10.1110/PS.073049407 Variant Set Distributions Mapped Variants
General Structure Information 2h2b TJP1 crystal structure of zo-1 pdz1 bound to a phage-derived ligand (wrrttyl) 1.6Å AUTH B.A.APPLETON,Y.ZHANG,P.WU,J.P.YIN,W.HUNZIKER,N.J.SKELTON,AUTH 2 S.S.SIDHU,C.WIESMANNTITL COMPARATIVE STRUCTURAL ANALYSIS OF THE ERBIN PDZ DOMAIN ANDTITL 2 THE FIRST PDZ DOMAIN OF ZO-1. INSIGHTS INTO DETERMINANTS OFTITL 3 PDZ DOMAIN SPECIFICITY.REF J.BIOL.CHEM. V. 281 22312 2006REFN ISSN 0021-9258PMID 16737969DOI 10.1074/JBC.M602901200 Variant […]
General Structure Information 2p3w HTRA3 crystal structure of the htra3 pdz domain bound to a phage-derived ligand (fgrwv) 1.7Å AUTH S.T.RUNYON,Y.ZHANG,B.A.APPLETON,S.L.SAZINSKY,P.WU,B.PAN,AUTH 2 C.WIESMANN,N.J.SKELTON,S.S.SIDHUTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PDZ DOMAINS OFTITL 2 HUMAN HTRA1 AND HTRA3.REF PROTEIN SCI. V. 16 2454 2007REFN ISSN 0961-8368PMID 17962403DOI 10.1110/PS.073049407 Variant Set Distributions Mapped Variants
General Structure Information 3qb1 IL2 interleukin-2 mutant d10 3.1Å AUTH A.M.LEVIN,D.L.BATES,A.M.RING,C.KRIEG,J.T.LIN,L.SU,I.MORAGA,AUTH 2 M.E.RAEBER,G.R.BOWMAN,P.NOVICK,V.S.PANDE,C.G.FATHMAN,AUTH 3 O.BOYMAN,K.C.GARCIATITL EXPLOITING A NATURAL CONFORMATIONAL SWITCH TO ENGINEER ANTITL 2 INTERLEUKIN-2 SUPERKINEREF NATURE V. 484 529 2012REFN ISSN 0028-0836PMID 22446627DOI 10.1038/NATURE10975 Variant Set Distributions Mapped Variants
General Structure Information 4aqp ATXN1 the structure of the axh domain of ataxin-1. 2.45Å AUTH C.DE CHIARA,M.REES,R.P.MENON,K.PAUWELS,C.LAWRENCE,AUTH 2 P.V.KONAREV,D.I.SVERGUN,S.R.MARTIN,Y.W.CHEN,A.PASTORETITL SELF-ASSEMBLY AND CONFORMATIONAL HETEROGENEITY OF THE AXHTITL 2 DOMAIN OF ATAXIN-1: AN UNUSUAL EXAMPLE OF A CHAMELEON FOLDREF BIOPHYS.J. V. 104 1304 2013REFN ISSN 0006-3495PMID 23528090DOI 10.1016/J.BPJ.2013.01.048 Variant Set Distributions Mapped Variants