Assessment of Structural Intolerance and Durability
General Structure Information 2hi4 CYP1A2 crystal structure of human microsomal p450 1a2 in complex with alpha-naphthoflavone 1.95Å AUTH S.SANSEN,J.K.YANO,R.L.REYNALD,G.A.SCHOCH,AUTH 2 K.J.GRIFFIN,C.D.STOUT,E.F.JOHNSONTITL ADAPTATIONS FOR THE OXIDATION OF POLYCYCLICTITL 2 AROMATIC HYDROCARBONS EXHIBITED BY THE STRUCTURETITL 3 OF HUMAN P450 1A2.REF J.BIOL.CHEM. V. 282 14348 2007REFN ISSN 0021-9258PMID 17311915DOI 10.1074/JBC.M611692200 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3rgk MB crystal structure of human myoglobin mutant k45r 1.65Å AUTH S.R.HUBBARD,S.G.LAMBRIGHT,S.G.BOXER,W.A.HENDRICKSONTITL X-RAY CRYSTAL STRUCTURE OF A RECOMBINANT HUMAN MYOGLOBINTITL 2 MUTANT AT 2.8 A RESOLUTIONREF J.MOL.BIOL. V. 20 215 1990REFN ISSN 0022-2836PMID 2342104 Variant Set Distributions Mapped Variants
General Structure Information 1dgb CAT human erythrocyte catalase 2.2Å AUTH C.D.PUTNAM,A.S.ARVAI,Y.BOURNE,J.A.TAINERTITL ACTIVE AND INHIBITED HUMAN CATALASE STRUCTURES:TITL 2 LIGAND AND NADPH BINDING AND CATALYTIC MECHANISM.REF J.MOL.BIOL. V. 296 295 2000REFN ISSN 0022-2836PMID 10656833DOI 10.1006/JMBI.1999.3458 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ner CYB5B structure of human type b cytochrome b5 1.45Å AUTH S.PARTHASARATHY,A.ALTUVE,S.TERZYAN,X.ZHANG,K.KUCZERA,AUTH 2 M.RIVERA,D.R.BENSONTITL ACCOMMODATING A NON-CONSERVATIVE INTERNAL MUTATION BYTITL 2 WATER-MEDIATED HYDROGEN-BONDING BETWEEN BETA-SHEET STRANDS:TITL 3 A COMPARISON OF HUMAN AND RAT TYPE B (MITOCHONDRIAL)TITL 4 CYTOCHROME B5REF BIOCHEMISTRY V. 50 5544 2011REFN ISSN 0006-2960PMID 21574570DOI 10.1021/BI2004729 Variant Set Distributions Mapped […]