Assessment of Structural Intolerance and Durability
General Structure Information 2ctr DNAJB9 solution structure of j-domain from human dnaj subfamily b menber 9 -1.0Å AUTH N.KOBAYASHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF J-DOMAIN FROM HUMAN DNAJTITL 2 SUBFAMILY B MENBER 9REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wi3 SATB2 solution structure of the homeodomain of kiaa1034 protein -1.0Å AUTH K.IZUMI,M.YOSHIDA,F.HAYASHI,R.HATTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEODOMAIN OF KIAA1034TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cra HOXB13 solution structure of the homeobox domain of human homeo box b13 -1.0Å AUTH K.SEIMIYA,F.HAYASHI,T.NAGASHIMA,M.YOSHIDA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OF HUMANTITL 2 HOMEO BOX B13REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2rc4 KAT6A crystal structure of the hat domain of the human moz protein 3.0Å AUTH M.A.HOLBERT,T.SIKORSKI,J.CARTEN,D.SNOWFLACK,S.HODAWADEKAR,AUTH 2 R.MARMORSTEINTITL THE HUMAN MONOCYTIC LEUKEMIA ZINC FINGER HISTONETITL 2 ACETYLTRANSFERASE DOMAIN CONTAINS DNA-BINDING ACTIVITYTITL 3 IMPLICATED IN CHROMATIN TARGETING.REF J.BIOL.CHEM. V. 282 36603 2007REFN ISSN 0021-9258PMID 17925393DOI 10.1074/JBC.M705812200 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2cto MAEL solution structure of the hmg box like domain from human hypothetical protein flj14904 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 Y.O.KAMATARI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX LIKE DOMAIN FROMTITL 2 HUMAN HYPOTHETICAL PROTEIN FLJ14904REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmx DNAJB8 solution structure of the j domain of dnaj homolog subfamily b member 8 -1.0Å AUTH S.OHNISHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE J DOMAIN OF DNAJ HOMOLOGTITL 2 SUBFAMILY B MEMBER 8REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qu6 IRF3 crystal structure of irf-3 dbd free form 2.3Å AUTH P.DE IOANNES,C.R.ESCALANTE,A.K.AGGARWALTITL STRUCTURES OF APO IRF-3 AND IRF-7 DNA BINDING DOMAINS:TITL 2 EFFECT OF LOOP L1 ON DNA BINDING.REF NUCLEIC ACIDS RES. V. 39 7300 2011REFN ISSN 0305-1048PMID 21596780DOI 10.1093/NAR/GKR325 Variant Set Distributions Mapped Variants
General Structure Information 3qu6 IRF3 crystal structure of irf-3 dbd free form 2.3Å AUTH P.DE IOANNES,C.R.ESCALANTE,A.K.AGGARWALTITL STRUCTURES OF APO IRF-3 AND IRF-7 DNA BINDING DOMAINS:TITL 2 EFFECT OF LOOP L1 ON DNA BINDING.REF NUCLEIC ACIDS RES. V. 39 7300 2011REFN ISSN 0305-1048PMID 21596780DOI 10.1093/NAR/GKR325 Variant Set Distributions Mapped Variants
General Structure Information 3d1n POU6F1 structure of human brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter 2.51Å AUTH J.H.PEREIRA,S.H.KIMTITL STRUCTURE OF HUMAN BRN-5 TRANSCRIPTION FACTOR INTITL 2 COMPLEX WITH CRH GENE PROMOTER.REF J.STRUCT.BIOL. V. 167 159 2009REFN ISSN 1047-8477PMID 19450691DOI 10.1016/J.JSB.2009.05.003 Variant Set Distributions Mapped Variants
General Structure Information 1xmk ADAR the crystal structure of the zb domain from the rna editing enzyme adar1 0.97Å AUTH A.ATHANASIADIS,D.PLACIDO,S.MAAS,B.A.BROWN II,AUTH 2 K.LOWENHAUPT,A.RICHTITL THE CRYSTAL STRUCTURE OF THE Z[BETA] DOMAIN OF THETITL 2 RNA-EDITING ENZYME ADAR1 REVEALS DISTINCTTITL 3 CONSERVED SURFACES AMONG Z-DOMAINS.REF J.MOL.BIOL. V. 351 496 2005REFN ISSN 0022-2836PMID 16023667DOI 10.1016/J.JMB.2005.06.028 Variant Set […]