Assessment of Structural Intolerance and Durability
General Structure Information 2g6b RAB26 crystal structure of human rab26 in complex with a gtp analogue 2.0Å AUTH J.WANG,W.TEMPEL,Y.SHEN,L.SHEN,D.YANIW,C.ARROWSMITH,AUTH 2 A.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB26 IN COMPLEX WITH ATITL 2 GTP ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ocb RAB9B crystal structure of human rab9b in complex with a gtp analogue 2.2Å AUTH B.HONG,L.SHEN,J.R.WALKER,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB9B IN COMPLEX WITH ATITL 2 GTP ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4i1o RAB1B crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 2.7Å AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 Variant Set Distributions Ripley’s […]
General Structure Information 2h57 ARL6 crystal structure of human adp-ribosylation factor-like 6 2.0Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,J.LEW,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN ADP-RIBOSYLATIONTITL 2 FACTOR-LIKE 6 (CASP TARGET)REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2atv RERG the crystal structure of human rerg in the gdp bound state 1.9Å AUTH A.P.TURNBULL,E.SALAH,G.SCHOCH,J.ELKINS,N.BURGESS,O.GILEADI,AUTH 2 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,AUTH 3 D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN RERG IN THE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2erx DIRAS2 crystal structure of diras2 in complex with gdp and inorganic phosphate 1.65Å AUTH E.PAPAGRIGORIOU,X.YANG,J.ELKINS,F.E.NIESEN,AUTH 2 N.BURGESS,E.SALAH,O.FEDOROV,L.J.BALL,F.VON DELFT,AUTH 3 M.SUNDSTROM,A.EDWARDS,C.ARROWSMITH,J.WEIGELT,AUTH 4 D.DOYLETITL CRYSTAL STRUCTURE OF DIRAS2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2cs4 RASSF8 solution structure of n-terminal domain of chromosome 12 open reading frame 2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF N-TERMINAL DOMAIN OFTITL 2 CHROMOSOME 12 OPEN READING FRAME 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ew1 RAB30 crystal structure of rab30 in complex with a gtp analogue 2.0Å AUTH J.WANG,Y.SHEN,S.ISMAIL,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.W.PARKTITL CRYSTAL STRUCTURE OF RAB30 IN COMPLEX WITH A GTPTITL 2 ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fg5 RAB31 crystal structure of human rab31 in complex with a gtp analogue 2.8Å AUTH J.WANG,W.TEMPEL,S.ISMAIL,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB31 IN COMPLEX WITH ATITL 2 GTP ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants