General Structure Information 2vxo GMPS human gmp synthetase in complex with xmp 2.5Å AUTH M.WELIN,L.LEHTIO,A.JOHANSSON,S.FLODIN,T.NYMAN,AUTH 2 L.TRESAUGUES,M.HAMMARSTROM,S.GRASLUND,P.NORDLUNDTITL SUBSTRATE SPECIFICITY AND OLIGOMERIZATION OF HUMANTITL 2 GMP SYNTHETASEREF J.MOL.BIOL. V. 425 4323 2013REFN ISSN 0022-2836PMID 23816837DOI 10.1016/J.JMB.2013.06.032 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1f5n GBP1 human guanylate binding protein-1 in complex with the gtp analogue, gmppnp. 1.7Å AUTH B.PRAKASH,L.RENAULT,G.J.PRAEFCKE,C.HERRMANN,AUTH 2 A.WITTINGHOFERTITL TRIPHOSPHATE STRUCTURE OF GUANYLATE-BINDINGTITL 2 PROTEIN 1 AND IMPLICATIONS FOR NUCLEOTIDE BINDINGTITL 3 AND GTPASE MECHANISM.REF EMBO J. V. 19 4555 2000REFN ISSN 0261-4189PMID 10970849DOI 10.1093/EMBOJ/19.17.4555 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4ijq HPRT1 human hypoxanthine-guanine phosphoribosyltransferase in complex with [(2-((guanine-9h-yl)methyl)propane-1,3-diyl)bis(oxy)]bis(methylene)) diphosphonic acid 2.0Å AUTH D.T.KEOUGH,P.SPACEK,D.HOCKOVA,T.TICHY,S.VRBKOVA,AUTH 2 L.SLAVETINSKA,Z.JANEBA,L.NAESENS,M.D.EDSTEIN,M.CHAVCHICH,AUTH 3 T.H.WANG,J.JERSEY,L.W.GUDDATTITL ACYCLIC NUCLEOSIDE PHOSPHONATES CONTAINING A SECONDTITL 2 PHOSPHONATE GROUP ARE POTENT INHIBITORS OF 6-OXOPURINETITL 3 PHOSPHORIBOSYLTRANSFERASES AND HAVE ANTIMALARIAL ACTIVITYREF J.MED.CHEM. V. 56 2513 2013REFN ISSN 0022-2623PMID 23448281DOI 10.1021/JM301893B Variant Set Distributions Pathogenic Proximity […]