Assessment of Structural Intolerance and Durability
General Structure Information 2d8s MARCH8 solution structure of the ring domain of the human cellular modulator of immune recognition protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE HUMANTITL 2 CELLULAR MODULATOR OF IMMUNE RECOGNITION PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2edv FRMPD1 solution structure of the pdz domain from human ferm and pdz domain containing 1 -1.0Å AUTH K.SEIMIYA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 FERM AND PDZ DOMAIN CONTAINING 1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2edr OBSCN solution structure of the ig-like domain (3361-3449) of human obscurin -1.0Å AUTH C.KUROSAKI,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (3361-3449) OF HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3pmi MUM1 pwwp domain of human mutated melanoma-associated antigen 1 2.82Å AUTH H.WU,H.ZENG,R.LAM,W.TEMPEL,M.F.AMAYA,C.XU,L.DOMBROVSKI,AUTH 2 W.QIU,Y.WANG,J.MINTITL STRUCTURAL AND HISTONE BINDING ABILITY CHARACTERIZATIONS OFTITL 2 HUMAN PWWP DOMAINS.REF PLOS ONE V. 6 18919 2011REFN ESSN 1932-6203PMID 21720545DOI 10.1371/JOURNAL.PONE.0018919 Variant Set Distributions Mapped Variants
General Structure Information 3eap ARHGAP11A crystal structure of the rhogap domain of arhgap11a 2.3Å AUTH Y.SHEN,L.SHEN,Y.TONG,W.TEMPEL,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF ARHGAP11AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1r79 DGKD solution structure of the c1 domain of the human diacylglycerol kinase delta -1.0Å AUTH K.MIYAMOTO,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C1 DOMAIN OF THE HUMANTITL 2 DIACYLGLYCEROL KINASE DELTAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3pp2 ARHGAP27 crystal structure of the pleckstrin homology domain of arhgap27 1.42Å AUTH L.SHEN,W.TEMPEL,Y.TONG,L.NEDYALKOVA,Y.LI,A.K.WERNIMONT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OFTITL 2 ARHGAP27REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3d8b FIGNL1 crystal structure of human fidgetin-like protein 1 in complex with adp 2.0Å AUTH T.KARLBERG,M.WISNIEWSKA,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,AUTH 4 I.JOHANSSON,A.KALLAS,T.KOTENYOVA,L.LEHTIO,M.MOCHE,AUTH 5 M.E.NILSSON,P.NORDLUND,T.NYMAN,K.OLESEN,C.PERSSON,AUTH 6 J.SAGEMARK,A.G.THORSELL,L.TRESAUGUES,S.VAN DEN BERG,M.WELIN,AUTH 7 M.WIKSTROM,H.SCHULERTITL HUMAN FIDGETIN-LIKE PROTEIN 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4jon CEP170 crystal structure of a centrosomal protein 170kda, transcript variant beta (cep170) from homo sapiens at 2.15 a resolution (psi community target, sundstrom) 2.15Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A CENTROSOMAL PROTEIN 170KDA,TITL 2 TRANSCRIPT VARIANT BETA (CEP170) FROM HOMO SAPIENS AT 2.15 ATITL 3 RESOLUTION […]
General Structure Information 4ld6 PWWP2B pwwp domain of human pwwp domain-containing protein 2b 1.7Å AUTH L.DOMBROVSKI,A.DONG,W.TEMPEL,P.LOPPNAU,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,P.J.BROWN,H.WU,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF PWWP DOMAIN OF HUMAN PWWPTITL 2 DOMAIN-CONTAINING PROTEIN 2BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants