Assessment of Structural Intolerance and Durability
General Structure Information 2z0u WWC1 crystal structure of c2 domain of kibra protein 2.2Å AUTH K.MURAYAMA,M.KATO-MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF C2 DOMAIN OF KIBRA PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wfv MAGI2 solution structure of the fifth pdz domain of human membrane associated guanylate kinase inverted-2 (kiaa0705 protein) -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH PDZ DOMAIN OFTITL 2 HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASETITL 3 INVERTED-2 (KIAA0705 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2css RIMS1 solution structure of the pdz domain of human kiaa0340 protein -1.0Å AUTH K.INOUE,X.-R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN OF HUMANTITL 2 KIAA0340 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1uep MAGI2 solution structure of the third pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3gge GIPC2 crystal structure of the pdz domain of pdz domain-containing protein gipc2 2.6Å AUTH A.CHAIKUAD,V.HOZJAN,W.YUE,C.COOPER,J.ELKINS,A.C.W.PIKE,AUTH 2 A.K.ROOS,P.FILIPPAKOPOULOS,F.VON DELFT,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PDZ DOMAIN-CONTAININGTITL 2 PROTEIN GIPC2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dip ZSWIM2 solution structure of the zz domain of zinc finger swim domain containing protein 2 -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZZ DOMAIN OF ZINC FINGERTITL 2 SWIM DOMAIN CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3dl2 UEVLD hexagonal structure of the ldh domain of human ubiquitin- conjugating enzyme e2-like isoform a 2.1Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,E.M.NEWMAN,AUTH 2 P.J.FINERTY JR.,C.BUTLER-COLE,C.BOUNTRA,AUTH 3 M.WOLKSTROM,C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 S.DHE-PAGANONTITL STRUCTURAL INVESTIGATION INTO THE L-LACTATETITL 2 DEHYDROGENASE DOMAIN OF HUMANTITL 3 UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tlp PBRM1 crystal structure of the fourth bromodomain of human poly-bromodomain containing protein 1 (pb1) 2.13Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 2eoh ZFP28 solution structure of the c2h2 type zinc finger (region 780- 812) of human zinc finger protein 28 homolog -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 780-812) OF HUMAN ZINC FINGER PROTEIN 28TITL 3 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4l7e HDDC2 three dimensional structure of mutant d78a of human hd domain- containing protein 2, genomics consortium (nesg) target hr6723 2.23Å AUTH A.KUZIN,M.SU,A..YAKUNIN,N.BELOGLAZOVA,J.SEETHARAMAN,AUTH 2 M.MAGLAQUI,R.XIAO,D.LEE,G.BROWN,R.FLICK,J.K.EVERETT,AUTH 3 T.B.ACTON,G.T.MONTELIONE,J.F.HUNT,L.TONG,AUTH 4 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6723REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]