Assessment of Structural Intolerance and Durability
General Structure Information 1pvh LIF crystal structure of leukemia inhibitory factor in complex with gp130 2.5Å AUTH M.J.BOULANGER,A.J.BANKOVICH,T.KORTEMME,D.BAKER,AUTH 2 K.C.GARCIATITL CONVERGENT MECHANISMS FOR RECOGNITION OF DIVERGENTTITL 2 CYTOKINES BY THE SHARED SIGNALING RECEPTOR GP130.REF MOL.CELL V. 12 577 2003REFN ISSN 1097-2765PMID 14527405DOI 10.1016/S1097-2765(03)00365-4 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2b90 IL4 crystal structure of the interleukin-4 variant t13dr85a 2.1Å AUTH M.KRAICH,M.KLEIN,E.PATINO,H.HARRER,J.NICKEL,W.SEBALD,AUTH 2 T.D.MUELLERTITL A MODULAR INTERFACE OF IL-4 ALLOWS FOR SCALABLE AFFINITYTITL 2 WITHOUT AFFECTING SPECIFICITY FOR THE IL-4 RECEPTORREF BMC BIOL. V. 4 13 2006REFN ESSN 1741-7007PMID 16640778DOI 10.1186/1741-7007-4-13 Variant Set Distributions Mapped Variants
General Structure Information 1v66 PIAS1 solution structure of human p53 binding domain of pias-1 -1.0Å AUTH S.OKUBO,F.HARA,Y.TSUCHIDA,S.SHIMOTAKAHARA,S.SUZUKI,AUTH 2 H.HATANAKA,S.YOKOYAMA,H.TANAKA,H.YASUDA,H.SHINDOTITL NMR STRUCTURE OF THE N-TERMINAL DOMAIN OF SUMOTITL 2 LIGASE PIAS1 AND ITS INTERACTION WITH TUMORTITL 3 SUPPRESSOR P53 AND A/T-RICH DNA OLIGOMERSREF J.BIOL.CHEM. V. 279 31455 2004REFN ISSN 0021-9258PMID 15133049DOI 10.1074/JBC.M403561200 Variant Set Distributions Mapped […]