Assessment of Structural Intolerance and Durability
General Structure Information 2xqn TES complex of the 2nd and 3rd lim domains of tes with the evh1 domain of mena and the n-terminal domain of actin-like protein arp7a 2.62Å AUTH B.BOEDA,P.P.KNOWLES,D.C.BRIGGS,J.MURRAY-RUST,E.SORIANO,AUTH 2 B.K.GARVALOV,N.Q.MCDONALD,M.WAYTITL MOLECULAR RECOGNITION OF THE TES LIM2-3 DOMAINS BY THETITL 2 ACTIN-RELATED PROTEIN ARP7A.REF J.BIOL.CHEM. V. 286 11543 2011REFN ISSN 0021-9258PMID 21278383DOI […]
General Structure Information 2xqn ENAH complex of the 2nd and 3rd lim domains of tes with the evh1 domain of mena and the n-terminal domain of actin-like protein arp7a 2.62Å AUTH B.BOEDA,P.P.KNOWLES,D.C.BRIGGS,J.MURRAY-RUST,E.SORIANO,AUTH 2 B.K.GARVALOV,N.Q.MCDONALD,M.WAYTITL MOLECULAR RECOGNITION OF THE TES LIM2-3 DOMAINS BY THETITL 2 ACTIN-RELATED PROTEIN ARP7A.REF J.BIOL.CHEM. V. 286 11543 2011REFN ISSN 0021-9258PMID 21278383DOI […]
General Structure Information 3u3f PTK2B structural basis for the interaction of pyk2 pat domain with paxillin ld motifs 3.1Å AUTH M.S.VANAROTTI,D.J.MILLER,C.D.GUIBAO,A.NOURSE,J.J.ZHENGTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO THE INTERACTIONTITL 2 BETWEEN PYK2 AND PAXILLIN LD MOTIFS.REF J.MOL.BIOL. V. 426 3985 2014REFN ISSN 0022-2836PMID 25174335DOI 10.1016/J.JMB.2014.08.014 Variant Set Distributions Mapped Variants
General Structure Information 4hi9 ILK 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at wavelength 0.91974 1.2Å AUTH A.L.STIEGLER,J.JAKONCIC,V.STOJANOFF,B.P.CHISWELL,AUTH 2 D.A.CALDERWOOD,T.J.BOGGONTITL 1.2 STRUCTURE OF INTEGRIN-LINKED KINASE ANKYRIN REPEATTITL 2 DOMAIN IN COMPLEX WITH PINCH1 LIM1 DOMAIN COLLECTED ATTITL 3 WAVELENGTH 0.91974REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2uvl BIRC3 human bir3 domain of baculoviral inhibitor of apoptosis repeat-containing 3 (birc3) 1.91Å AUTH M.D.HERMAN,M.MOCHE,S.FLODIN,M.WELIN,L.TRESAUGUES,AUTH 2 I.JOHANSSON,M.NILSSON,P.NORDLUND,T.NYMANTITL STRUCTURES OF BIR DOMAINS FROM HUMAN NAIP AND CIAP2.REF ACTA CRYSTALLOGR.,SECT.F V. 65 1091 2009REFN ISSN 1744-3091PMID 19923725DOI 10.1107/S1744309109038597 Variant Set Distributions Mapped Variants
General Structure Information 4ny0 PTK2 crystal structure of ferm domain of human focal adhesion kinase 2.8Å AUTH K.BRAMI-CHERRIER,N.GERVASI,D.ARSENIEVA,K.WALKIEWICZ,AUTH 2 M.C.BOUTTERIN,A.ORTEGA,P.G.LEONARD,B.SEANTIER,L.GASMI,AUTH 3 T.BOUCEBA,G.KADARE,J.A.GIRAULT,S.T.AROLDTITL FAK DIMERIZATION CONTROLS ITS KINASE-DEPENDENT FUNCTIONS ATTITL 2 FOCAL ADHESIONS.REF EMBO J. V. 33 356 2014REFN ISSN 0261-4189PMID 24480479DOI 10.1002/EMBJ.201386399 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]