Assessment of Structural Intolerance and Durability
General Structure Information 2vig ACADS crystal structure of human short-chain acyl coa dehydrogenase 1.9Å AUTH A.C.W.PIKE,N.PANTIC,E.PARIZOTTO,O.GILEADI,AUTH 2 E.UGOCHUKWU,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SHORT-CHAIN ACYL COATITL 2 DEHYDROGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1v16 BCKDHA crosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine 1.9Å AUTH J.LI,R.M.WYNN,M.MACHIUS,J.L.CHUANG,S.KARTHIKEYAN,AUTH 2 D.R.TOMCHICK,D.T.CHUANGTITL CROSS-TALK BETWEEN THIAMIN DIPHOSPHATE BINDING ANDTITL 2 PHOSPHORYLATION LOOP CONFORMATION IN HUMAN BRANCHED-CHAINTITL 3 {ALPHA}-KETO ACID DECARBOXYLASE/DEHYDROGENASEREF J.BIOL.CHEM. V. 279 32968 2004REFN ISSN 0021-9258PMID 15166214DOI 10.1074/JBC.M403611200 Variant Set Distributions Pathogenic Proximity Analysis […]
General Structure Information 1egd ACADM structure of t255e, e376g mutant of human medium chain acyl- coa dehydrogenase 2.4Å AUTH H.J.LEE,M.WANG,R.PASCHKE,A.NANDY,S.GHISLA,J.J.KIMTITL CRYSTAL STRUCTURES OF THE WILD TYPE AND THETITL 2 GLU376GLY/THR255GLU MUTANT OF HUMAN MEDIUM-CHAINTITL 3 ACYL-COA DEHYDROGENASE: INFLUENCE OF THE LOCATIONTITL 4 OF THE CATALYTIC BASE ON SUBSTRATE SPECIFICITY.REF BIOCHEMISTRY V. 35 12412 1996REFN ISSN […]
General Structure Information 1umk CYB5R3 the structure of human erythrocyte nadh-cytochrome b5 reductase 1.75Å AUTH S.BANDO,T.TAKANO,T.YUBISUI,K.SHIRABE,M.TAKESHITA,AUTH 2 A.NAKAGAWATITL STRUCTURE OF HUMAN ERYTHROCYTE NADH-CYTOCHROME B5TITL 2 REDUCTASE.REF ACTA CRYSTALLOGR.,SECT.D V. 60 1929 2004REFN ISSN 0907-4449PMID 15502298DOI 10.1107/S0907444904020645 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3llk QSOX1 sulfhydryl oxidase fragment of human qsox1 2.0Å AUTH A.ALON,E.J.HECKLER,C.THORPE,D.FASSTITL QSOX CONTAINS A PSEUDO-DIMER OF FUNCTIONAL AND DEGENERATETITL 2 SULFHYDRYL OXIDASE DOMAINS.REF FEBS LETT. V. 584 1521 2010REFN ISSN 0014-5793PMID 20211621DOI 10.1016/J.FEBSLET.2010.03.001 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants