Assessment of Structural Intolerance and Durability
General Structure Information 4ndg APTX human aprataxin (aptx) bound to rna-dna and zn – adenosine vanadate transition state mimic complex 2.54Å AUTH P.TUMBALE,J.S.WILLIAMS,M.J.SCHELLENBERG,T.A.KUNKEL,AUTH 2 R.S.WILLIAMSTITL APRATAXIN RESOLVES ADENYLATED RNA-DNA JUNCTIONS TO MAINTAINTITL 2 GENOME INTEGRITY.REF NATURE V. 506 111 2013REFN ISSN 0028-0836PMID 24362567DOI 10.1038/NATURE12824 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2co8 MICAL1 solution structures of the lim domain of human nedd9 interacting protein with calponin homology and lim domains -1.0Å AUTH M.SATO,T.TOMIZAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE LIM DOMAIN OF HUMANTITL 2 NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGYTITL 3 AND LIM DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rpp MBNL2 solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2 -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions Mapped Variants
General Structure Information 1wig ABLIM2 solution structure of rsgi ruh-019, a lim domain of actin binding lim protein 2 (kiaa1808 protein) from human cdna -1.0Å AUTH T.ABE,H.HIROTA,S.KOSHIBA,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-019, A LIM DOMAINTITL 2 OF ACTIN BINDING LIM PROTEIN 2 (KIAA1808 PROTEIN)TITL 3 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 1×68 FHL5 solution structures of the c-terminal lim domain of human fhl5 protein -1.0Å AUTH N.NAMEKI,A.SASAGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C-TERMINAL LIM DOMAINTITL 2 OF HUMAN FHL5 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dmi TSHZ3 solution structure of the first and the second zf-c2h2 like domains of human teashirt homolog 3 -1.0Å AUTH H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND THE SECONDTITL 2 ZF-C2H2 LIKE DOMAINS OF HUMAN TEASHIRT HOMOLOG 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1ldj CUL1 structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex 3.0Å AUTH N.ZHENG,B.A.SCHULMAN,L.SONG,J.J.MILLER,P.D.JEFFREY,AUTH 2 P.WANG,C.CHU,D.M.KOEPP,S.J.ELLEDGE,M.PAGANO,AUTH 3 R.C.CONAWAY,J.W.CONAWAY,J.W.HARPER,N.P.PAVLETICHTITL STRUCTURE OF THE CUL1-RBX1-SKP1-F BOXSKP2 SCFTITL 2 UBIQUITIN LIGASE COMPLEX.REF NATURE V. 416 703 2002REFN ISSN 0028-0836PMID 11961546DOI 10.1038/416703A Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2bkf NBR1 structure of the pb1 domain of nbr1 1.56Å AUTH S.MUELLER,I.KURSULA,P.ZOU,M.WILMANNSTITL CRYSTAL STRUCTURE OF THE PB1 DOMAIN OF NBR1REF FEBS LETT. V. 580 341 2006REFN ISSN 0014-5793PMID 16376336DOI 10.1016/J.FEBSLET.2005.12.021 Variant Set Distributions Mapped Variants
General Structure Information 2m85 SHPRH phd domain from human shprh -1.0Å AUTH L.E.MACHADO,Y.PUSTOVALOVA,A.C.KILE,A.POZHIDAEVA,AUTH 2 K.A.CIMPRICH,F.C.ALMEIDA,I.BEZSONOVA,D.M.KORZHNEVTITL PHD DOMAIN FROM HUMAN SHPRH.REF J.BIOMOL.NMR V. 56 393 2013REFN ISSN 0925-2738PMID 23907177DOI 10.1007/S10858-013-9758-2 Variant Set Distributions Mapped Variants
General Structure Information 2kkt ATXN7L3 solution structure of the sca7 domain of human ataxin-7-l3 protein -1.0Å AUTH J.BONNET,Y.WANG,A.ATKINSON,J.KOFFLER,C.ROMIER,A.HAMICHE,AUTH 2 L.TORA,D.DEVYS,B.KIEFFERTITL HISTONE DEUBIQUITINATION BY SAGA IS MODULATED BY ANTITL 2 ATYPICAL ZINC FINGER DOMAIN OF ATAXIN-7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants