Assessment of Structural Intolerance and Durability
General Structure Information 2f15 PRKAB2 glycogen-binding domain of the amp-activated protein kinase beta2 subunit 2.0Å AUTH J.R.WALKER,L.WYBENGA-GROOT,P.J.FINERTY JR.,AUTH 2 E.NEWMAN,F.M.MACKENZIE,J.WEIGELT,M.SUNDSTROM,AUTH 3 C.ARROWSMITH,A.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURE OF THE GLYCOGEN-BINDING DOMAIN OF THETITL 2 AMP-ACTIVATED PROTEIN KINASE BETA2 SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kxo HPGDS an orally active inhibitor bound at the active site of hpgds 2.1Å AUTH C.P.CARRON,J.I.TRUJILLO,K.L.OLSON,W.HUANG,B.C.HAMPER,T.DICE,AUTH 2 B.E.NEAL,M.J.PELC,J.DAY,D.C.ROHRER,J.R.KIEFER,J.B.MOON,AUTH 3 B.A.SCHWEITZER,T.D.BLAKE,S.R.TURNER,R.WOERNDLE,B.L.CASE,AUTH 4 C.P.BONO,V.M.DILWORTH,C.L.FUNCKES-SHIPPY,B.L.HOOD,AUTH 5 G.M.JEROME,C.M.KORNMEIER,M.R.RADABAUGH,M.L.WILLIAMS,AUTH 6 M.S.DAVIES,C.D.WEGNER,D.J.WELSCH,W.M.ABRAHAM,C.J.WARREN,AUTH 7 M.E.DOWTY,F.HUA,A.ZUTSHI,J.Z.YANG,A.THORARENSENTITL DISCOVERY OF AN ORAL POTENT SELECTIVE INHIBITOR OFTITL 2 HEMATOPOIETIC PROSTAGLANDIN D SYNTHASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3gid ACACB the biotin carboxylase (bc) domain of human acetyl-coa carboxylase 2 (acc2) in complex with soraphen a 2.3Å AUTH B.RAYMER,M.KAVANA,A.PRICE,B.WANG,L.CORCORAN,R.KULATHILA,AUTH 2 J.GROARKE,T.MANNTITL SYNTHESIS AND CHARACTERIZATION OF A BODIPY-LABELEDTITL 2 DERIVATIVE OF SORAPHEN A THAT BINDS TO ACETYL-COATITL 3 CARBOXYLASE.REF BIOORG.MED.CHEM.LETT. V. 19 2804 2009REFN ISSN 0960-894XPMID 19359168DOI 10.1016/J.BMCL.2009.03.107 Variant Set Distributions […]