Assessment of Structural Intolerance and Durability
General Structure Information 4fgu LGMN crystal structure of prolegumain 3.9Å AUTH E.DALL,H.BRANDSTETTERTITL MECHANISTIC AND STRUCTURAL STUDIES ON LEGUMAIN EXPLAIN ITSTITL 2 ZYMOGENICITY, DISTINCT ACTIVATION PATHWAYS, AND REGULATION.REF PROC.NATL.ACAD.SCI.USA V. 110 10940 2013REFN ISSN 0027-8424PMID 23776206DOI 10.1073/PNAS.1300686110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ddu PREP prolyl oligopeptidase with gsk552 1.56Å AUTH C.D.HAFFNER,C.J.DIAZ,A.B.MILLER,R.A.REID,K.P.MADAUSS,AUTH 2 A.HASSELL,M.H.HANLON,D.J.PORTER,J.D.BECHERER,L.H.CARTERTITL PYRROLIDINYL PYRIDONE AND PYRAZINONE ANALOGUES AS POTENTTITL 2 INHIBITORS OF PROLYL OLIGOPEPTIDASE (POP)REF BIOORG.MED.CHEM.LETT. V. 18 4360 2008REFN ISSN 0960-894XPMID 18606544DOI 10.1016/J.BMCL.2008.06.067 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants