Assessment of Structural Intolerance and Durability
General Structure Information 2jxc EPS15 structure of the eps15-eh2 stonin2 complex -1.0Å AUTH J.RUMPF,B.SIMON,N.JUNG,T.MARITZEN,V.HAUCKE,M.SATTLER,AUTH 2 Y.GROEMPINGTITL STRUCTURE OF THE EPS15-STONIN2 COMPLEX PROVIDES A MOLECULARTITL 2 EXPLANATION FOR EH-DOMAIN LIGAND SPECIFICITY.REF EMBO J. V. 27 558 2008REFN ISSN 0261-4189PMID 18200045DOI 10.1038/SJ.EMBOJ.7601980 Variant Set Distributions Mapped Variants
General Structure Information 2r83 SYT1 crystal structure analysis of human synaptotagmin 1 c2a-c2b 2.7Å AUTH K.L.FUSON,M.MONTES,J.J.ROBERT,R.B.SUTTONTITL STRUCTURE OF HUMAN SYNAPTOTAGMIN 1 C2AB IN THETITL 2 ABSENCE OF CA2+ REVEALS A NOVEL DOMAIN ASSOCIATION.REF BIOCHEMISTRY V. 46 13041 2007REFN ISSN 0006-2960PMID 17956130DOI 10.1021/BI701651K Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3kq4 GIF structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Mapped Variants
General Structure Information 2bme RAB4A high resolution structure of gppnhp-bound human rab4a 1.57Å AUTH S.K.HUBER,A.J.SCHEIDIGTITL HIGH RESOLUTION CRYSTAL STRUCTURES OF HUMAN RAB4ATITL 2 IN ITS ACTIVE AND INACTIVE CONFORMATIONS.REF FEBS LETT. V. 579 2821 2005REFN ISSN 0014-5793PMID 15907487DOI 10.1016/J.FEBSLET.2005.04.020 Variant Set Distributions Mapped Variants
General Structure Information 1iu1 AP1G1 crystal structure of human gamma1-adaptin ear domain 1.8Å AUTH T.NOGI,Y.SHIBA,M.KAWASAKI,T.SHIBA,N.MATSUGAKI,AUTH 2 N.IGARASHI,M.SUZUKI,R.KATO,H.TAKATSU,K.NAKAYAMA,AUTH 3 S.WAKATSUKITITL STRUCTURAL BASIS FOR THE ACCESSORY PROTEINTITL 2 RECRUITMENT BY THE GAMMA-ADAPTIN EAR DOMAIN.REF NAT.STRUCT.BIOL. V. 9 527 2002REFN ISSN 1072-8368PMID 12042876 Variant Set Distributions Mapped Variants
General Structure Information 3kq4 CUBN structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dxc APBB1 crystal structure of the intracellular domain of human app in complex with fe65-ptb2 2.1Å AUTH J.RADZIMANOWSKI,B.SIMON,M.SATTLER,K.BEYREUTHER,AUTH 2 I.SINNING,K.WILDTITL STRUCTURE OF THE INTRACELLULAR DOMAIN OF THETITL 2 AMYLOID PRECURSOR PROTEIN IN COMPLEX WITHTITL 3 FE65-PTB2.REF EMBO REP. V. 9 1134 2008REFN ISSN 1469-221XPMID 18833287DOI 10.1038/EMBOR.2008.188 Variant Set Distributions Mapped Variants
General Structure Information 2no2 HIP1 crystal structure of the dllrkn-containing coiled-coil domain of huntingtin-interacting protein 1 2.8Å AUTH J.A.YBE,S.MISHRA,S.HELMS,J.NIXTITL CRYSTAL STRUCTURE AT 2.8 A OF THETITL 2 DLLRKN-CONTAINING COILED-COIL DOMAIN OFTITL 3 HUNTINGTIN-INTERACTING PROTEIN 1 (HIP1) REVEALS ATITL 4 SURFACE SUITABLE FOR CLATHRIN LIGHT CHAIN BINDINGREF J.MOL.BIOL. V. 367 8 2007REFN ISSN 0022-2836PMID 17257618DOI 10.1016/J.JMB.2006.12.052 […]