Assessment of Structural Intolerance and Durability
General Structure Information 2jw5 POLL polymerase lambda brct domain -1.0Å AUTH G.A.MUELLER,A.F.MOON,E.F.DEROSE,B.J.DAVIS,AUTH 2 D.A.RAMSDEN,L.C.PEDERSEN,R.E.LONDONTITL POLYMERASE LAMBDA BRCT DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2le9 S100A13 ragec2-s100a13 tetrameric complex -1.0Å AUTH S.G.RANI,S.K.MOHAN,C.YUTITL INTERACTION OF S100A13 WITH RECEPTOR FOR ADVANCED GLYCATIONTITL 2 END PRODUCTS (RAGE) C2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ndg APTX human aprataxin (aptx) bound to rna-dna and zn – adenosine vanadate transition state mimic complex 2.54Å AUTH P.TUMBALE,J.S.WILLIAMS,M.J.SCHELLENBERG,T.A.KUNKEL,AUTH 2 R.S.WILLIAMSTITL APRATAXIN RESOLVES ADENYLATED RNA-DNA JUNCTIONS TO MAINTAINTITL 2 GENOME INTEGRITY.REF NATURE V. 506 111 2013REFN ISSN 0028-0836PMID 24362567DOI 10.1038/NATURE12824 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3q2t CPSF6 crystal structure of cfim68 rrm/cfim25/rna complex 3.06Å AUTH Q.YANG,M.COSENO,G.M.GILMARTIN,S.DOUBLIETITL CRYSTAL STRUCTURE OF A HUMAN CLEAVAGE FACTORTITL 2 CFI(M)25/CFI(M)68/RNA COMPLEX PROVIDES AN INSIGHT INTOTITL 3 POLY(A) SITE RECOGNITION AND RNA LOOPING.REF STRUCTURE V. 19 368 2011REFN ISSN 0969-2126PMID 21295486DOI 10.1016/J.STR.2010.12.021 Variant Set Distributions Mapped Variants
General Structure Information 3w1g LIG4 crystal structure of human dna ligase iv-artemis complex (native) 2.55Å AUTH T.OCHI,X.GU,T.L.BLUNDELLTITL STRUCTURE OF THE CATALYTIC REGION OF DNA LIGASE IV INTITL 2 COMPLEX WITH AN ARTEMIS FRAGMENT SHEDS LIGHT ONTITL 3 DOUBLE-STRAND BREAK REPAIRREF STRUCTURE V. 21 672 2013REFN ISSN 0969-2126PMID 23523427DOI 10.1016/J.STR.2013.02.014 Variant Set Distributions Ripley’s K Analysis […]