General Structure Information 1d5f UBE3A structure of an e6ap-ubch7 complex: insights into the ubiquitination pathway 2.8Å AUTH L.HUANG,E.KINNUCAN,G.WANG,S.BEAUDENON,P.M.HOWLEY,AUTH 2 J.M.HUIBREGTSE,N.P.PAVLETICHTITL STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTOTITL 2 UBIQUITINATION BY THE E2-E3 ENZYME CASCADE.REF SCIENCE V. 286 1321 1999REFN ISSN 0036-8075PMID 10558980DOI 10.1126/SCIENCE.286.5443.1321 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4f52 RBX1 structure of a glomulin-rbx1-cul1 complex 3.0Å AUTH D.M.DUDA,J.L.OLSZEWSKI,A.E.TRON,M.HAMMEL,L.J.LAMBERT,AUTH 2 M.B.WADDELL,T.MITTAG,J.A.DECAPRIO,B.A.SCHULMANTITL STRUCTURE OF A GLOMULIN-RBX1-CUL1 COMPLEX: INHIBITION OF ATITL 2 RING E3 LIGASE THROUGH MASKING OF ITS E2-BINDING SURFACE.REF MOL.CELL V. 47 371 2012REFN ISSN 1097-2765PMID 22748924DOI 10.1016/J.MOLCEL.2012.05.044 Variant Set Distributions Mapped Variants
General Structure Information 3sqv UBE2L3 crystal structure of e. coli o157:h7 e3 ubiquitin ligase, nlel, with a human e2, ubch7 3.3Å AUTH D.Y.LIN,J.DIAO,J.CHENTITL CRYSTAL STRUCTURES OF TWO BACTERIAL HECT-LIKE E3 LIGASES INTITL 2 COMPLEX WITH A HUMAN E2 REVEAL ATOMIC DETAILS OFTITL 3 PATHOGEN-HOST INTERACTIONS.REF PROC.NATL.ACAD.SCI.USA V. 109 1925 2012REFN ISSN 0027-8424PMID 22308380DOI 10.1073/PNAS.1115025109 Variant […]
General Structure Information 2m3o NEDD4 structure and dynamics of a human nedd4 ww domain-enac complex -1.0Å AUTH R.BOBBY,K.MEDINI,P.NEUDECKER,T.V.LEE,M.A.BRIMBLE,AUTH 2 F.J.MCDONALD,J.S.LOTT,A.J.DINGLEYTITL STRUCTURE AND DYNAMICS OF HUMAN NEDD4-1 WW3 IN COMPLEX WITHTITL 2 THE ALPHA ENAC PY MOTIF.REF BIOCHIM.BIOPHYS.ACTA V.1834 1632 2013REFN ISSN 0006-3002PMID 23665454DOI 10.1016/J.BBAPAP.2013.04.031 Variant Set Distributions Mapped Variants
General Structure Information 3uio RANBP2 complex between human rangap1-sumo2, ubc9 and the ir1 domain from ranbp2 containing ir2 motif ii 2.6Å AUTH J.R.GAREAU,D.REVERTER,C.D.LIMATITL DETERMINANTS OF SMALL UBIQUITIN-LIKE MODIFIER 1 (SUMO1)TITL 2 PROTEIN SPECIFICITY, E3 LIGASE, AND SUMO-RANGAP1 BINDINGTITL 3 ACTIVITIES OF NUCLEOPORIN RANBP2.REF J.BIOL.CHEM. V. 287 4740 2012REFN ISSN 0021-9258PMID 22194619DOI 10.1074/JBC.M111.321141 Variant Set Distributions […]
General Structure Information 2gwf USP8 structure of a usp8-nrdp1 complex 2.3Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,F.MACKENZIE,AUTH 2 E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESE INTERACTION,TITL 2 AND INHIBITED CATALYTIC DOMAIN CONFORMATION OF THETITL 3 UBIQUITIN-SPECIFIC PROTEASE 8 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Mapped Variants
General Structure Information 1zmd DLD crystal structure of human dihydrolipoamide dehydrogenase complexed to nadh 2.08Å AUTH C.A.BRAUTIGAM,J.L.CHUANG,D.R.TOMCHICK,M.MACHIUS,AUTH 2 D.T.CHUANGTITL CRYSTAL STRUCTURE OF HUMAN DIHYDROLIPOAMIDETITL 2 DEHYDROGENASE: NAD+/NADH BINDING AND THETITL 3 STRUCTURAL BASIS OF DISEASE-CAUSING MUTATIONSREF J.MOL.BIOL. V. 350 543 2005REFN ISSN 0022-2836PMID 15946682DOI 10.1016/J.JMB.2005.05.014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3hu6 SPOP structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1 2.7Å AUTH M.ZHUANG,M.F.CALABRESE,J.LIU,M.B.WADDELL,A.NOURSE,AUTH 2 M.HAMMEL,D.J.MILLER,H.WALDEN,D.M.DUDA,S.N.SEYEDIN,AUTH 3 T.HOGGARD,J.W.HARPER,K.P.WHITE,B.A.SCHULMANTITL STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTSTITL 2 INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITINTITL 3 LIGASES.REF MOL.CELL V. 36 39 2009REFN ISSN 1097-2765PMID 19818708DOI 10.1016/J.MOLCEL.2009.09.022 Variant Set Distributions Ripley’s K Analysis Plots […]