Assessment of Structural Intolerance and Durability
General Structure Information 2eqx KBTBD4 solution structure of the back domain of kelch repeat and btb domain-containing protein 4 -1.0Å AUTH M.IMAI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BACK DOMAIN OF KELCHTITL 2 REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wvo NANS solution structure of rsgi ruh-029, an antifreeze protein like domain in human n-acetylneuraminic acid phosphate synthase gene. -1.0Å AUTH T.HAMADA,Y.ITO,T.ABE,F.HAYASHI,P.GUNTERT,M.INOUE,AUTH 2 T.KIGAWA,T.TERADA,M.SHIROUZU,M.YOSHIDA,A.TANAKA,AUTH 3 S.SUGANO,S.YOKOYAMA,H.HIROTATITL SOLUTION STRUCTURE OF THE ANTIFREEZE-LIKE DOMAINTITL 2 OF HUMAN SIALIC ACID SYNTHASEREF PROTEIN SCI. V. 15 1010 2006REFN ISSN 0961-8368PMID 16597820DOI 10.1110/PS.051700406 Variant Set Distributions Mapped […]
General Structure Information 4edj GORASP2 crystal structure of the grasp55 grasp domain with a phosphomimetic mutation (s189d) 1.9Å AUTH S.T.TRUSCHEL,M.ZHANG,C.BACHERT,M.R.MACBETH,A.D.LINSTEDTTITL ALLOSTERIC REGULATION OF GRASP PROTEIN-DEPENDENT GOLGITITL 2 MEMBRANE TETHERING BY MITOTIC PHOSPHORYLATION.REF J.BIOL.CHEM. V. 287 19870 2012REFN ISSN 0021-9258PMID 22523075DOI 10.1074/JBC.M111.326256 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1x4w ZFAND3 solution structure of the zf-an1 domain from human hypothetical protein flj13222 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-AN1 DOMAIN FROM HUMANTITL 2 HYPOTHETICAL PROTEIN FLJ13222REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2v4u CTPS2 human ctp synthetase 2 – glutaminase domain in complex with 5-oxo-l-norleucine 2.3Å AUTH M.WELIN,M.MOCHE,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 L.LEHTIO,M.E.NILSSON,T.NYMAN,K.OLESEN,C.PERSSON,AUTH 6 J.SAGEMARK,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 S.VAN DEN BERG,M.WISNIEWSKA,J.WEIGELT,M.WIKSTROM,AUTH 8 P.NORDLUNDTITL HUMAN CTP SYNTHETASE 2 – GLUTAMINASE DOMAIN INTITL 2 COMPLEX WITH 5-OXO-L-NORLEUCINEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dk6 PARP11 solution structure of wwe domain in poly (adp-ribose) polymerase family, member 11 (parp 11) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF WWE DOMAIN IN POLYTITL 2 (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 11 (PARP 11)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ee0 PCDH9 solution structures of the ca domain of human protocadherin 9 -1.0Å AUTH M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE CA DOMAIN OF HUMANTITL 2 PROTOCADHERIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dah UBQLN3 solution structure of the c-terminal uba domain in the human ubiquilin 3 -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL UBA DOMAIN INTITL 2 THE HUMAN UBIQUILIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ed0 ABI2 solution structure of the sh3 domain of abl interactor 2 (abelson interactor 2) -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,K.SAITO,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF ABLTITL 2 INTERACTOR 2 (ABELSON INTERACTOR 2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2khx DROSHA drosha double-stranded rna binding motif -1.0Å AUTH G.A.MUELLER,M.T.MILLER,E.F.DEROSE,M.GHOSH,R.E.LONDON,AUTH 2 T.M.HALLTITL SOLUTION STRUCTURE OF THE DROSHA DOUBLE-STRANDED RNA-BINDINGTITL 2 DOMAIN.REF SILENCE V. 1 2 2010REFN ESSN 1758-907XPMID 20226070DOI 10.1186/1758-907X-1-2 Variant Set Distributions Mapped Variants