General Structure Information 3l2p LIG3 human dna ligase iii recognizes dna ends by dynamic switching between two dna bound states 3.0Å AUTH E.COTNER-GOHARA,I.K.KIM,M.HAMMEL,J.A.TAINER,A.E.TOMKINSON,AUTH 2 T.ELLENBERGERTITL HUMAN DNA LIGASE III RECOGNIZES DNA ENDS BY DYNAMICTITL 2 SWITCHING BETWEEN TWO DNA-BOUND STATES.REF BIOCHEMISTRY V. 49 6165 2010REFN ISSN 0006-2960PMID 20518483DOI 10.1021/BI100503W Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1jkw CCNH structure of cyclin mcs2 2.6Å AUTH G.ANDERSEN,A.POTERSZMAN,J.M.EGLY,D.MORAS,AUTH 2 J.C.THIERRYTITL THE CRYSTAL STRUCTURE OF HUMAN CYCLIN H.REF FEBS LETT. V. 397 65 1996REFN ISSN 0014-5793PMID 8941715DOI 10.1016/S0014-5793(96)01143-X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2x2r KIF11 crystal structure of human kinesin eg5 in complex with (r)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid 2.2Å AUTH H.Y.K.KAAN,J.WEISS,D.MENGER,V.ULAGANATHAN,K.TKOCZ,C.LAGGNER,AUTH 2 F.POPOWYCZ,B.JOSEPH,F.KOZIELSKITITL STRUCTURE-ACTIVITY RELATIONSHIP AND MULTIDRUG RESISTANCETITL 2 STUDY OF NEW S-TRITYL-L-CYSTEINE DERIVATIVES AS INHIBITORSTITL 3 OF EG5.REF J.MED.CHEM. V. 54 1576 2011REFN ISSN 0022-2623PMID 21344920DOI 10.1021/JM100991M Variant Set Distributions Mapped Variants
General Structure Information 3l82 TERF1 x-ray crystal structure of trf1 and fbx4 complex 2.4Å AUTH Z.ZENG,W.WANG,Y.YANG,Y.CHEN,X.YANG,J.A.DIEHL,X.LIU,M.LEITITL STRUCTURAL BASIS OF SELECTIVE UBIQUITINATION OF TRF1 BYTITL 2 SCF(FBX4)REF DEV.CELL V. 18 214 2010REFN ISSN 1534-5807PMID 20159592DOI 10.1016/J.DEVCEL.2010.01.007 Variant Set Distributions Mapped Variants
General Structure Information 2w5a NEK2 human nek2 kinase adp-bound 1.55Å AUTH I.WESTWOOD,D.M.CHEARY,J.E.BAXTER,M.W.RICHARDS,AUTH 2 R.L.VAN MONTFORT,A.M.FRY,R.BAYLISSTITL INSIGHTS INTO THE CONFORMATIONAL VARIABILITY ANDTITL 2 REGULATION OF HUMAN NEK2 KINASE.REF J.MOL.BIOL. V. 386 476 2009REFN ISSN 0022-2836PMID 19124027DOI 10.1016/J.JMB.2008.12.033 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ii6 LIG4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Ripley’s K […]
General Structure Information 1cks CKS2 human ckshs2 atomic structure: a role for its hexameric assembly in cell cycle control 2.1Å AUTH H.E.PARGE,A.S.ARVAI,D.J.MURTARI,S.I.REED,J.A.TAINERTITL HUMAN CKSHS2 ATOMIC STRUCTURE: A ROLE FOR ITS HEXAMERICTITL 2 ASSEMBLY IN CELL CYCLE CONTROL.REF SCIENCE V. 262 387 1993REFN ISSN 0036-8075PMID 8211159 Variant Set Distributions Mapped Variants