Assessment of Structural Intolerance and Durability
General Structure Information 3fg6 SCIN structure of the c-terminus of adseverin 3.0Å AUTH S.CHUMNARNSILPA,W.L.LEE,S.NAG,B.KANNAN,M.LARSSON,AUTH 2 L.D.BURTNICK,R.C.ROBINSONTITL THE CRYSTAL STRUCTURE OF THE C-TERMINUS OF ADSEVERIN REVEALSTITL 2 THE ACTIN-BINDING INTERFACE.REF PROC.NATL.ACAD.SCI.USA V. 106 13719 2009REFN ISSN 0027-8424PMID 19666531DOI 10.1073/PNAS.0812383106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3dad FHOD1 crystal structure of the n-terminal regulatory domains of the formin fhod1 2.3Å AUTH A.SCHULTE,B.STOLP,A.SCHONICHEN,O.PYLYPENKO,A.RAK,AUTH 2 O.T.FACKLER,M.GEYERTITL THE HUMAN FORMIN FHOD1 CONTAINS A BIPARTITETITL 2 STRUCTURE OF FH3 AND GTPASE-BINDING DOMAINSTITL 3 REQUIRED FOR ACTIVATION.REF STRUCTURE V. 16 1313 2008REFN ISSN 0969-2126PMID 18786395DOI 10.1016/J.STR.2008.06.008 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3l43 DNM3 crystal structure of the dynamin 3 gtpase domain bound with gdp 2.27Å AUTH S.YANG,W.TEMPEL,Y.TONG,L.NEDYALKOVA,X.GUAN,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE DYNAMIN 3 GTPASE DOMAIN BOUND WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2cp3 CLIP2 solution structure of the 2nd cap-gly domain in human clip- 115/cyln2 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 2ND CAP-GLY DOMAIN INTITL 2 HUMAN CLIP-115/CYLN2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kdg MYOT solution structure of the 1st ig domain of myotilin -1.0Å AUTH O.HEIKKINEN,P.PERMI,H.KOSKELA,O.CARPEN,J.YLANNE,AUTH 2 I.KILPELAINENTITL SOLUTION STRUCTURE OF THE FIRST IMMUNOGLOBULINTITL 2 DOMAIN OF HUMAN MYOTILINREF J.BIOMOL.NMR V. 44 107 2009REFN ISSN 0925-2738PMID 19418025DOI 10.1007/S10858-009-9320-4 Variant Set Distributions Mapped Variants
General Structure Information 2kkq MYOT solution nmr structure of the ig-like c2-type 2 domain of human myotilin. northeast structural genomics target hr3158. -1.0Å AUTH P.ROSSI,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE IG-LIKE C2-TYPE 2TITL 2 DOMAIN OF HUMAN MYOTILIN. NORTHEAST STRUCTURALTITL 3 GENOMICS TARGET HR3158.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xqn TES complex of the 2nd and 3rd lim domains of tes with the evh1 domain of mena and the n-terminal domain of actin-like protein arp7a 2.62Å AUTH B.BOEDA,P.P.KNOWLES,D.C.BRIGGS,J.MURRAY-RUST,E.SORIANO,AUTH 2 B.K.GARVALOV,N.Q.MCDONALD,M.WAYTITL MOLECULAR RECOGNITION OF THE TES LIM2-3 DOMAINS BY THETITL 2 ACTIN-RELATED PROTEIN ARP7A.REF J.BIOL.CHEM. V. 286 11543 2011REFN ISSN 0021-9258PMID 21278383DOI […]
General Structure Information 3l82 FBXO4 x-ray crystal structure of trf1 and fbx4 complex 2.4Å AUTH Z.ZENG,W.WANG,Y.YANG,Y.CHEN,X.YANG,J.A.DIEHL,X.LIU,M.LEITITL STRUCTURAL BASIS OF SELECTIVE UBIQUITINATION OF TRF1 BYTITL 2 SCF(FBX4)REF DEV.CELL V. 18 214 2010REFN ISSN 1534-5807PMID 20159592DOI 10.1016/J.DEVCEL.2010.01.007 Variant Set Distributions Mapped Variants
General Structure Information 2os6 ARHGEF12 solution structure of larg pdz domain in complex with c- terminal octa-peptide of plexin b1 -1.0Å AUTH J.LIU,H.HUANG,Y.YANGTITL SOLUTION STRUCTURE OF THE LARG PDZ DOMAIN INTITL 2 COMPLEX WITH C-TERMINAL PEPTIDE OF PLEXIN B1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants